Brazilian Journal of Anesthesiology
https://app.periodikos.com.br/journal/rba/article/doi/10.1016/j.bjane.2015.05.002
Brazilian Journal of Anesthesiology
Scientific Article

Sufentanil in combination with low-dose hyperbaric bupivacaine in spinal anesthesia for cesarean section: a randomized clinical trial

Associação de sufentanil a dose reduzida de bupivacaína hiperbárica em raquianestesia para cesariana: ensaio clínico randomizado

Alexandre Dubeux Dourado; Ruy Leite de Melo Lins Filho; Raphaella Amanda Maria Leite Fernandes; Marcelo Cavalcanti de Sá Gondim; Emmanuel Victor Magalhães Nogueira

Downloads: 0
Views: 936

Abstract

Abstract A double blind randomized clinical trial of sufentanil as an adjunct in spinal anesthesia for cesarean section and, thereby, be able to reduce the dose of bupivacaine, a local anesthetic, with the same result of an anesthetic block with higher doses but with fewer perioperative side effects, such as hypotension.

Keywords

Sufentanil, Spinal anesthesia, Bupivacaine, Hyperbaric, Cesarean section

Resumo

Resumo Ensaio clínico randomizado duplamente encoberto sobre o uso do sufentanil como adjuvante em raquianestesia para cesariana e, possibilitando a redução da dose do anestésico local, a bupivacaína, com o mesmo resultado de bloqueio anestésico com doses mais elevadas, mas com menos efeitos colaterais no perioperatório, como hipotensão.

Palavras-chave

Sufentanil, Raquianestesia, Bupivacaína, Hiperbárica, Cesariana

References

Birnbach DJ, Browne IM. Anesthesia for obstetrics. Miller's anesthesia. 2010;2:2219-20.

Tsen LC. Anesthesia for obstetric care and gynecologic surgery. Anesthesiology. 2008:1480-4.

Arzola C, Wieczorek PM. Efficacy of low-dose bupivacaine in spinal anaesthesia for caesarean delivery: systematic review and meta-analysis. Br J Anaesth. 2011;107:308-18.

Roofthooft E, Van de Velde M. Low-dose spinal anaesthesia for caesarean section to prevent spinal-induced hypotension. Curr Opin Anaesthesiol. 2008;21:259-62.

Chinachoti T, Tritakarn T. Prospective study of hypotension and bradycardia during spinal anesthesia with bupivacaine: incidence and risk factors, part two. J Med Assoc Thai. 2007;90:492-501.

Cyna AM, Andrew M, Emmett RS. Techniques for preventing hypotension during spinal anaesthesia for caesarean section. Cochrane Database Syst Rev. 2006:CD002251.

Vercauteren MP, Coppejans HC, Hoffmann VH. Prevention of hypotension by single 5 mg dose of ephedrine during small dose spinal anesthesia in prehydrated cesarean delivery patients. Anesth Analg. 2000;90:324-7.

Fan SZ, Susetio L, Wang YP. Low dose of intrathecal hyperbaric bupivacaine combined with epidural lidocaine for cesarean section - a balance block technique. Anesth Analg. 1994;78:474-8.

Choi DH, Ahn HJ, Kim MH. Bupivacaine-sparing effect of fentanyl in spinal anesthesia for cesarean delivery. Reg Anesth Pain Med. 2000;25:240-5.

Dyer RA, Joubert IA. Low-dose spinal anaesthesia for caesarean section. Curr Opin Anaesthesiol. 2004;17:301-8.

Crowhurst JA, Birnbach DJ. Small-dose neuraxial block: heading toward the new millennium. Anesth Analg. 2000;90:241-2.

Ben DB, Miller G, Gavriel R. Low dose bupivacaine-fentanyl spinal anesthesia for cesarean delivery. Reg Anesth Pain Med. 2000;25:235-9.

Choi DH, Ahn HJ, Kim JA. Combined low-dose spinal-epidural anesthesia versus single shot spinal anesthesia for elective cesarean delivery. Int J Obstet Anesth. 2006;15:13-7.

Ghazi A, Raja Y. Combined low-dose spinal-epidural anaesthesia versus single-shot spinal anaesthesia for elective caesarean delivery. Int J Obstet Anesth. 2007;16:90-1.

Veena A, Amit A, Jagdish SP. Comparison of intrathecal sufentanil and morphine in addition to bupivacaine for caesarean section under spinal anesthesia. Anaesth Pain Intensive Care. 2010;14:99-101.

Dahlgren G, Hultstrand C, Jakobsson J. Intrathecal sufentanil, fentanyl, or placebo added to bupivacaine for cesarean section. Anesth Analg. 1997;85:1288-93.

Bang YS, Chung KH, Lee JH. Comparison of clinical effects according to the dosage of sufentanil added to 0.5% hyperbaric bupivacaine for spinal anesthesia in patients undergoing cesarean section. Korean J Anesthesiol. 2012;63:321-6.

Braga AA, Frias JAF, Braga FS. Raquianestesia em operação cesariana. Emprego da associação de bupivacaína hiperbárica (10 mg) a diferentes adjuvantes. Rev Bras Anestesiol. 2012;62:775-87.

Lee JH, Chung KH, Lee JY. Comparison of fentanyl and sufentanil added to 0.5% hyperbaric bupivacaine for spinal anesthesia in patients undergoing cesarean section. Korean J Anesthesiol. 2011;60:103-8.

Bogra J, Arora N, Srivastava P. Synergistic effect of intrathecal fentanyl and bupivacaine in spinal anesthesia for cesarean section. BMC Anesthesiol. 2005;5:5.

Nermin KG, Alp G, Gurkan T. Intrathecal morphine in anesthesia for cesarean delivery: dose-response relationship for combinations of low-dose intrathecal morphine and spinal bupivacaine. J Clin Anesth. 2008;20:180-5.

5dcd594a0e88256d11bf58f1 rba Articles
Links & Downloads

Braz J Anesthesiol

Share this page
Page Sections