Effects of the cryolipolysis using the advanced redux method in the treatment of localized adiposity
Roseane Débora Barbosa Soares, Rodrigo Marcel Valentim da Silva, Júlio Costa e Silva, Bruna Figueiredo Pinto, Stephan Queiroga Farias, Ana Lívia Eufrázio de Medeiros Farias, Eneida de Morais Carreiro, Claudete Arruda Maciel de Queiroz, Patrícia Froes Meyer
Abstract
Background: Among the techniques used in clinical practice to reduce localized adiposity, cryolipolysis has been highlighted, which is a non-invasive method capable of reducing the thickness of the adipose tissue without damage to the surrounding tissues. However, several associations of techniques suggest an intensification of the results, associating cryolipolysis with other treatments, and the most common is ultracavitation (UCV) or radiofrequency (RF) and massage. Objective: To investigate the effects of cryolipolysis associated with UCV and RF on localized adiposity. Methods: This is a blinded and controlled clinical trial. The sample was composed of 30 females divided into 2 groups of 15: one group received cryolipolysis application in the abdominal region, and performed 1 session of drainage weekly; while another group performed the cryolipolysis and then 8 applications of UCV associated with RF and modeling massage (protocol named Advanced Redux Method – ARM), once a week. The parameters used in cryolipolysis were: temperature: -7ºC; suction pressure: 30 kpa; and application time: 50 min. For the UCV, the parameters were time of 8 minutes, 30w of potency and intensity of 10 w/cm2 . After cryolipolysis, a follow-up of 2 months was performed to verify the changes related to weight, perimeter and thickness of the adipose tissue, measured by ultrasonography. The reassessments were performed 30 and 60 days after the cryolipolysis. Results: It was observed that the ARM promoted a greater reduction of adiposity located in the abdominal region, in the plicometry, perimetry and ultrasonography variables (p<0.05). In the analysis of the questionnaires the ARM group showed lower edema, pain, ecchymosis after application when compared to the group associated only with the drainage. The percentage of satisfaction was also higher in the ARM group. Conclusion: Therefore, it can be observed that the association of UCV, RF and modeling massage through the ARM promoted a higher reduction in adiposity than the group that exclusively performed the cryolipolysis treatment with lymphatic drainage.
Keywords
References
1- Lipner SR. Cryolipolysis for the treatment of submental fat: Review of the literature. J Cosmet Dermatol. 2018;17(2):145-151.
2- Derrick CD, Shridharani SM, Broyles JM. The Safety and Efficacy of Cryolipolysis: A Systematic Review of Available Literature. Aesthet Surg J. 2015;35(7):830-6.
3- Munavalli GS, Panchaprateep R. Cryolipolysis for Targeted Fat Reduction and Improved Appearance of the Enlarged Male Breast. Dermatol Surg. 2015;41(9):1043-51.
4- Krueger N, Mai SV, Luebberding S, Sadick NS. Cryolipolysis for noninvasive body contouring: clinical efficacy and patient satisfaction. Clin Cosmet Investig Dermatol. 2014;26;7:201-5.
5- Friedmann DP. A review of the aesthetic treatment of abdominal subcutaneous adipose tissue: background, implications, and therapeutic options. Dermatol Surg. 2015;41(1):18-34.
6- Quistgaard Ju. The European Aesthetic Guide Spring 2010. Available from: http://digital.miinews. com/publication/?i=34631&page=1
7- Nassab R. The Evidence Behind Noninvasive Body Contouring Devices. Aesthet Surg J. 2015;35(3):279-93.
8- Mulholland RS, Paul MD, Chalfoun C. Noninvasive body contouring with radiofrequency, ultrasound, cryolipolysis, and low-level laser therapy. Clin Plast Surg. 2011 ;38(3):503-20.
9- Friedmann DP. A review of the aesthetic treatment of abdominal subcutaneous adipose tissue: background, implications, and therapeutic options. Dermatol Surg. 2015 ;41(1):18-34.
10- McDaniel D, Fritz K, Machovcova A, Bernardy J. A focused monopolar radiofrequency causes apoptosis: a porcine model. J Drugs Dermatol. 2014;13(11):1336-40.
11- Boisnic S, Divaris M, Nelson AA, Gharavi NM, Lask GP. A clinical and biological evaluation of a novel, noninvasive radiofrequency device for the long-term reduction of adipose tissue. Lasers Surg Med. 2014 ;46(2):94-103.
12- Boey GE, Wasilenchuk JL. Enhanced clinical outcome with manual massage following cryolipolysis treatment: a 4-month study of safety and efficacy. Lasers Surg Med. 2014 ;46(1):20-6.
13- Sasaki GH, Abelev N, Tevez-Ortiz A. Noninvasive selective cryolipolysis and reperfusion recovery for localized natural fat reduction and contouring. Aesthet Surg J. 2014;34(3):420-31.
14- Segot-Chicq E, Compan-Zaouati D, Wolkenstein P, Consoli S, Rodary C, Delvigne V, Guillou V, Poli F. Development and validation of a questionnaire to evaluate how cosmetic product for oily skin is able to improve wellbeing in women. J Eur Acad Dermatol Venereol. 2007 ;21(9):1181-6.
15- Meyer PF, Furtado ACG, Morais SFT, de Araujo Neto LG, Silva RMV, Medeiros ML, Queiroz., CAM. Effects of Cryolipolysis on Abdominal Adiposity of Women. Cryoletters. 2017;38 (5):379-386(8).
16- Sasaki GH; Abelev N; Tevez-Ortiz A. Noninvasive selective cryolipolysis and reperfusion recovery for localized natural fat reduction and contouring. Aesthetic Surgery Journal. 2014;34(3):420-431.
17- Ferraro GA, De Francesco F, NicolettI G, Rossano F, D’andrea F. Histologic effects of external ultrasound-assisted lipectomy on adipose tissue. Aesthetic Plast Surg 2008;32(1):111-5.
18- Eldesoky E E, Mohamed AG, Samir MM. Ultrasound cavitation versus cryolipolysis for non‐invasive body contouring. Australasian J Derm. 2016, 57 (4): 288-93.
19- Silva RMV, Meyer PF, Santos BR, Oliveira Félix, JL, Ronzio OA. Efectos del ultrasonido de alta potência en la adiposidad localizada. Fisioterapia. 2015;37(2): 55-59.
20- Meyer PF, Carvalho MGF, Andrade LL, Lopes RNS, Delgado AM, Araújo HG, Nóbrega LLM, Nóbrega MM, Barrichelo PA, Silva RMV. Efeitos da ultracavitação no tecido adiposo de coelhos. Fisioter. Bras;2012;13(2):106-111.
21- Ronzio AO, Meyer PF, Medeiros TD, Gurjão JB. Efectos de latransferenciaelectrica capacitiva eneltejidodermico y adiposo. Fisioterapia. 2009;31(4):131-136.
22- Vanaman, Monique, Guillen, Sabrina Fabi, Carruthers, Jean Carruthers. Complications in the Cosmetic Dermatology Patient: A Review and Our Experience. American Society for Dermatologic Surgery,2016;4 2: 1.
23- Gonçalves CS, Madeira JC, Silva MDD. Terapia combinada associada à drenagem linfática reduz lipodistrofia localizada no abdômen de mulheres jovens. ConScientiae Saúde, 2017;16(2): 281-288.
24- Miwa H, Kino M, Han LK, Takaoka K, Tsujita T, Furuhata H et al. Effect of ultrasound application on fat mobilization. Pathophysiology. 2002;(9): 13-19.
25- Vieira Nunes M, Costa Silva, F, Ramiro Moreira JA. Criolipólise: pré e póstratamento eletroterapêutico. Fisioterapia Brasil 2018;18.6:750-56.
26- Lipner SR. Cryolipolysis for the treatment of submental fat: Review of the literature. J Cosmet Dermatol. 2018;17(2):145-151.
27- Ortiz AE, Avram MM. Noninvasive body contouring: cryolipolysis and ultrasound. Semin Cutan Med Surg. 2015;34(3):129-33.
28- Loap S, Lathe R. Mechanism Underlying Tissue Cryotherapy to Combat Obesity/Overweight: Triggering Thermogenesis. J Obes. 2018; 5789647.