Brazilian Journal of Anesthesiology
https://app.periodikos.com.br/journal/rba/article/doi/10.1590/S0034-70942011000600002
Brazilian Journal of Anesthesiology
Scientific Article

Flor de Citrus aurantium e ansiedade pré-operatória

Citrus aurantium Blossom and Preoperative Anxiety

Mahmood Akhlaghi; Gholamreza Shabanian; Mahmoud Rafieian-Kopaei; Neda Parvin; Mitra Saadat; Mohsen Akhlaghi

http://dx.doi.org/10.1590/S0034-70942011000600002 Braz J Anesthesiol, vol.61, n6, p.707-712, 2011
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Resumo

JUSTIFICATIVA E OBJETIVOS: Reduzir a ansiedade é muito importante antes da operação. A visita no pré-operatório e a utilização de pré-medicação são os métodos mais populares para se atingir esse objetivo, mas o papel da pré-medicação ansiolítica permanece incerto e os efeitos colaterais no pós-operatório podem partir de uma pré-medicação de rotina. Citrus aurantium é usado como medicina alternativa em alguns países para tratar a ansiedade. Recentemente, o papel ansiolítico dessa planta medicinal foi estabelecido em um estudo realizado em modelo animal. O objetivo deste estudo foi avaliar o efeito ansiolítico da flor de Citrus aurantium sobre a ansiedade pré-operatória. MÉTODOS: Foram estudados 60 pacientes ASA I submetidos a uma pequena cirurgia. Em um desenho randomizado e duplo-cego, dois grupos de 30 pacientes receberam uma das seguintes MPA oral duas horas antes da indução da anestesia: 1) Citrus aurantium destilado 1 mL.kg-1 (Grupo C); 2) solução salina 1 mL.kg-1 como placebo (Grupo P). A ansiedade foi medida antes e após pré-medicação com o Inventário de Ansiedade Traço-Estado (IDATE) e a Escala de Ansiedade e Informação Pré-Operatória de Amsterdam (APAIS) antes da operação. RESULTADOS: Após pré-medicação, tanto o IDATE quanto as escalas APAIS estavam diminuídos no Grupo C (p < 0,05), embora não tenham apresentado alterações significativas no Grupo P. CONCLUSÕES:Citrus aurantium pode mostrar-se eficaz na redução da ansiedade pré-operatória em cirurgias de pequeno porte.

Palavras-chave

ANESTÉSICOS, CIRURGIA, CIRURGIA

Abstract

ACKGROUND AND OBJECTIVES: Reducing anxiety is very important before operation. Preoperative visit and use of premedication are popular methods to achieve this goal, but the role of anxiolytic premedication remains unclear and postoperative side-effects may result from routine premedication. Citrus aurantium is used as an alternative medicine in some countries to treat anxiety, and recently the anxiolytic role of this medicinal plant was established in an animal model study. The aim of this study was to assess the anxiolytic effect of Citrus aurantium blossom on preoperative anxiety. METHODS: We studied 60 ASA I patients undergoing minor operation. In a randomized double-blind design, two groups of 30 patients received one of the following oral premedication two hours before induction of anesthesia: 1) Citrus aurantium blossom distillate 1 mL.kg-1 (C-group); 2) Saline solution 1 mL.kg-1 as placebo (P-group). Anxiety was measured before and after premedication using the Spielberger state-trait anxiety inventory (STAI-state) and the Amsterdam preoperative anxiety and information scale (APAIS) before operation. RESULTS: After premedication, both the STAI-state and the APAIS scales were decreased in C-group (p < 0.05); while exhibiting no significant changes in P-group. CONCLUSIONS: Citrus aurantium blossom may be effective in terms of reduction in preoperative anxiety before minor operation.

Keywords

Citrus, Flowers, Preoperative Care, Anxiety, Ambulatory Surgical Procedures

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