Brazilian Journal of Anesthesiology
https://app.periodikos.com.br/journal/rba/article/doi/10.1590/S0034-70942010000600003
Brazilian Journal of Anesthesiology
Scientific Article

Sedação consciente para endoscopia digestiva alta realizada por médicos endoscopistas

Conscious sedation for upper digestive endoscopy performed by endoscopists

Ana Laura Colle Kauling; Giovani de Figueiredo Locks; Guilherme Muriano Brunharo; Viriato João Leal da Cunha; Maria Cristina Simões de Almeida

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Resumo

JUSTIFICATIVA E OBJETIVOS: A sedação consciente na prática ambulatorial, embora comum, não é isenta de riscos. Este trabalho teve por objetivo avaliar a pressão arterial, a frequência cardíaca e a saturação periférica de oxigênio em pacientes submetidos à sedação consciente para endoscopia digestiva alta, realizada por médicos endoscopistas. MÉTODOS: Foram selecionados 105 pacientes de ambos os sexos, com idade mínima de 18 anos, estado físico ASA I a III, submetidos a endoscopia digestiva alta sob sedação consciente. Os pacientes foram monitorados com medidas de pressão arterial não invasiva, oximetria de pulso e frequência cardíaca, registradas antes, durante e após o exame. A sedação foi administrada com os fármacos midazolam e/ou meperidina. RESULTADOS: As variações de saturação de oxigênio, pressão arterial e frequência cardíaca ao longo do tempo não foram estatisticamente significativas. Entretanto, observou-se incidência de hipóxia de 41,9%; em 53,3% dos casos, houve hipotensão arterial e taquicardia em 25,6%. Os pacientes obesos demonstraram-se mais suscetíveis à hipóxia e à hipotensão que aqueles não obesos. CONCLUSÕES: A ocorrência de hipóxia e hipotensão arterial é comum nos exames de endoscopia digestiva alta sob sedação consciente quando utilizados midazolam e meperidina associados. Pacientes obesos demonstraram-se mais suscetíveis à hipoxemia e à hipotensão arterial.

Palavras-chave

COMPLICAÇÕES, COMPLICAÇÕES, EXAMES DIAGNÓSTICOS, endoscopia digestiva, MEDICAÇÃO PRÉ-ANESTÉSICA, MEDICAÇÃO PRÉ-ANESTÉSICA, SEDAÇÃO

Abstract

BACKGROUND AND OBJECTIVES: Conscious sedation in the ambulatory setting albeit common is not risk-free. The present study aimed at evaluating the blood pressure, heart rate and peripheral oxygen saturation in patients submitted to conscious sedation for upper digestive endoscopy performed by endoscopists. METHODS: A total of 105 patients of both sexes were selected, aged 18 and older, physical status ASA I to III, submitted to upper digestive endoscopy under conscious sedation. The patients were monitored through noninvasive blood pressure measurements, pulse oximetry and heart rate recorded before, during and after the examination. The sedation was carried out with midazolam or meperidine. RESULTS: The variations in oxygen saturation, blood pressure and heart rate throughout time were not statistically significant. However, an incidence of hypoxia of 41.9% was observed; 53.3% of the cases presented arterial hypotension and 25.6% presented tachycardia. Obese patients were more prone to hypoxia and hypotension than those non obese. CONCLUSIONS: The occurrence of hypoxia and arterial hypotension is common in upper digestive endoscopic examinations under conscious sedation when midazolam and meperidine are associated. Obese patients demonstrated to be more susceptible to hypoxemia and arterial hypotension.

Keywords

COMPLICATIONS, COMPLICATIONS, DIAGNOSTIC ASSESSMENT, digestive endoscopy, PRE-ANESTHETIC MEDICATION, PRE-ANESTHETIC MEDICATION, SEDATION

References

Owings MF, Kozak LJ. Ambulatory and inpatient procedures in the United States, 1996. Vital Health Stat. 1998;13(139):1-119.

Deckert D, Zecha-Stallinger A, Haas T. Anesthesie ausserhalb des Zentral-OP. Anaesthesist. 2007;56:1028-1030, 1032-1037.

Fanning RM. Monitoring during sedation given by non-anaesthetic doctors. Anaesthesia. 2008;63:370-374.

Cohen LB, Delegge MH, Aisenberg J. AGA Institute review of endoscopic sedation. Gastroenterology. 2007;133:675-701.

Wang CY, Ling LC, Cardosa MS. Hypoxia during upper gastrointestinal endoscopy with and without sedation and the effect of preoxygenation on oxygen saturation. Anaesthesia. 2000;55:654-658.

Cohen LB. Patient monitoring during gastrointestinal endoscopy: why, when, and how?. Gastrointest Endosc Clin N Am. 2008;18:651-663.

Allgayer H, Pohl C, Kruis W. Arterial oxygen desaturation during endoscopic ultrasonography combined with gastroscopy: a safety evaluation in out-patients. Endoscopy. 1999;31:447-451.

Patel S, Vargo JJ, Khandwala F. Deep sedation occurs frequently during elective endoscopy with meperidine and midazolam. Am J Gastroenterol. 2005;100:2689-2695.

Patterson KW, Noonan N, Keeling NW. Hypoxemia during outpatient gastrointestinal endoscopy: the effects of sedation and supplemental oxygen. J Clin Anesth. 1995;7:136-140.

Rex DK. Review article: moderate sedation for endoscopy: sedation regimens for non-anaesthesiologists. Aliment Pharmacol Ther. 2006;24:163-171.

Lichtenstein DR, Jagannath S, Baron TH. Sedation and anesthesia in GI endoscopy. . 2008;68:815-826.

Casati A, Putzu M. Anesthesia in the obese patient: pharmacokinetic considerations. J Clin Anesth. 2005;17:134-145.

Cheah MH, Kam PC. Obesity: basic science and medical aspects relevant to anaesthetists. Anaesthesia. 2005;60:1009-1021.

Ristikankare M, Julkunen R, Heikkinen M. Sedation, topical pharyngeal anesthesia and cardiorespiratory safety during gastroscopy. J Clin Gastroenterol. 2006;40:899-905.

Young CC, Prielipp RC. Benzodiazepines in the intensive care unit. Crit Care Clin. 2001;17:843-862.

Horn E, Nesbit SA. Pharmacology and pharmacokinetics of sedatives and analgesics. Gastrointest Endosc Clin N Am. 2004;14:247-268.

Oliveira Filho GR, Turazzi Filho J, Owczarzak Júnior D. Efeitos circulatórios da associação de baixas doses de fentanil ao midazolam durante a indução anestésica e intubação traqueal. Rev Bras Anestesiol. 1990;40:395-399.

Osinaike BB, Akere A, Olajumoke TO. Cardiorespiratory changes during upper gastrointestinal endoscopy. Afr Health Sci. 2007;7(2):115-119.

Yetkin G, Oba S, Uludag M. Effects of sedation during upper gastrointestinal endoscopy on endocrine response and cardiorespiratory function. Braz J Med Biol Res. 2007;40:1647-1652.

Cohen LB, Wecsler JS, Gaetano JN. Endoscopic sedation in the United States: results from a nationwide survey. Am J Gastroenterol. 2006;101:967-974.

Quine MA, Bell GD, McCloy RF. Prospective audit of upper gastrointestinal endoscopy in two regions of England: safety, staffing, and sedation methods. Gut. 1995;36:462-467.

Bell GD. Premedication, preparation, and surveillance. Endoscopy. 2000;32:92-100.

American Society of Anesthesiologists Task Force on Sedation and Analgesia by Non-Anesthesiologists: Practice guidelines for sedation and analgesia by non-anesthesiologists. Anesthesiology. 2002;96:1004-1017.

Bryson EO, Sejpal D. Anesthesia in remote locations: radiology and beyond, international anesthesiology clinics: gastroenterology: endoscopy, colonoscopy, and ERCP. Int Anesthesiol Clin. 2009;47:69-80.

Bittinger M, Forst H, MessmanN H. Propofol in der gastroenterologischen Endoskopie: Zeit für einen Paradigmenwechsel?. Z Gastroenterol. 2004;42:470-474.

Heuss LT, Schnieper P, Drewe J. - Risk stratification and safe administration of propofol by registered nurses supervised by the gastroenterologist: a prospective observational study of more than 2000 cases. Gastrointest Endosc. 2003;57:664-671.

Heuss LT, Schnieper P, Drewe J. Conscious sedation with propofol in elderly patients: a prospective evaluation. Aliment Pharmacol Ther. 2003;17:1493-1501.

Kulling D, Rothenbuhler R, Inauen W. Safety of nonanesthetist sedation with propofol for outpatient colonoscopy and esophagogastroduodenoscopy. Endoscopy. 2003;35:679-682.

Walker JA, McIntyre RD, Schleinitz PF. Nurse-administered propofol sedation without anesthesia specialists in 9152 endoscopic cases in an ambulatory surgery center. Am J Gastroenterol. 2003;98:1744-1750.

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