Quimioterapia e anestesia

Márcio Augusto Lacerda

doi:10.1590/S0034-70942001000300009

Review Article

Quimioterapia e anestesia

Chemotherapy and anesthesia

Márcio Augusto Lacerda

http://dx.doi.org/10.1590/S0034-70942001000300009 Braz J Anesthesiol, vol.51, n3, p.250-270, 2001

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Resumo

JUSTIFICATIVA E OBJETIVOS: A quimioterapia é um dos principais tipos de tratamento oferecido a pacientes com câncer, mas ainda causam importantes efeitos colaterais, reversíveis ou não. Para os anestesiologistas, conhecer estas drogas, complicações e interações medicamentosas, é de importância capital em cirurgias com pacientes em tratamento de neoplasias. CONTEÚDO: Nesta revisão apresentam-se os diferentes tipos de quimioterápicos atualmente utilizados, a classificação farmacológica, repercussões orgânicas, interações com outras substâncias, e a conduta anestésica mais apropriada frente a elas, objetivando reduzir a morbi-mortalidade perioperatória nestes pacientes. CONCLUSÕES: O conhecimento, pelo anestesiologista, das formas de tratamento, das características farmacológicas destas substâncias, seus efeitos adversos, lesões estruturais e possíveis interações medicamentosas por elas geradas e potencializadas pelas várias técnicas anestésicas hoje empregadas, pode certamente reduzir a morbi-mortalidade peri-operatória destes pacientes.

Palavras-chave

DROGAS, Interação: quimioterápicos

Abstract

BACKGROUND AND OBJECTIVES: Chemotherapy is one of the main treatment available for cancer patients, but is still causing important side effects, reversible or not. Knowing such drugs, complications and interactions is critical for the anesthesiologist during surgeries in patients under cancer treatment. CONTENTS: This review presents the different types of chemotherapy agents currently used, their pharmacological classification, organic repercussions, interactions with other drugs and the most adequate anesthetic technique aiming at decreasing perioperative morbidity and mortality. CONCLUSIONS: The anesthesiologist awareness of types of treatment, pharmacological properties of such substances, their adverse effects, structural lesions and possible drug interactions created by them and exacerbated by several current anesthetic techniques may certainly decrease perioperative morbidity and mortality.

Keywords

DRUGS, Interation: chemotherapic

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Quimioterapia e anestesia

Chemotherapy and anesthesia

Márcio Augusto Lacerda

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