Brazilian Journal of Anesthesiology
https://app.periodikos.com.br/journal/rba/article/doi/10.1016/j.bjane.2026.844795
Brazilian Journal of Anesthesiology
Review Article

Artificial intelligence in cardiopulmonary resuscitation: a systematic review

Inteligência artificial na ressuscitação cardiopulmonar: uma revisão sistemática

Diogenes de Oliveira Silva, Giorgio Pretto, Saul Dominici, Antonio Carlos Aguiar Brandão, Plínio da Cunha Leal

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Abstract

Cardiac arrest remains a major cause of mortality and neurological disability, and its management depends on rapid recognition, effective resuscitation, and accurate post-arrest prognostication. Artificial intelligence (AI) has been increasingly investigated as a tool to support these stages of care. This narrative review summarizes recent evidence on AI applications in cardiac arrest, including prediction, recognition, intra-arrest support, prognostication, and cardiovascular risk stratification. Searches were conducted in PubMed/MEDLINE, Google Scholar, EMBASE, Scopus, IEEE Xplore, and ScienceDirect for studies published from January 2000 to June 2025. Studies addressing AI, machine learning, or deep learning in cardiac arrest-related contexts were descriptively synthesized according to clinical application, AI methodology, and care setting. Overall, 59 studies were included. Six application categories were identified: early prediction of cardiac arrest or clinical deterioration (n = 16), cardiac arrest recognition and emergency response activation (n = 3), intra-arrest CPR and defibrillation support (n = 6), post-cardiac arrest prognostication (n = 20), risk stratification for sudden cardiac death and malignant arrhythmias (n = 11), and related cardiovascular or perioperative prognostic models (n = 3). Deep learning and neural-network-based approaches were the most frequent methodologies (n = 35), followed by traditional machine learning (n = 18) and natural language processing (n = 6). AI showed particular promise for ECG-based prediction, temporal clinical trajectories, emergency call interpretation, waveform and defibrillation analyses, and neurological or mortality prognostication after cardiac arrest. However, the evidence remains heterogeneous, with many studies relying on retrospective datasets, selected populations, and limited external or prospective validation.

Keywords

Artificial intelligence; Cardiopulmonary resuscitation; Clinical decision support systems; Emergency medical services; Heart arrest; Machine learning

Resumo

A parada cardíaca continua sendo uma das principais causas de mortalidade e incapacidade neurológica, e seu manejo depende do reconhecimento rápido, de uma ressuscitação eficaz e da determinação precisa do prognóstico pós-parada. A inteligência artificial (IA) tem sido cada vez mais investigada como uma ferramenta de apoio a essas etapas da assistência. O objetivo desta revisão narrativa foi sintetizar as evidências recentes sobre as aplicações de IA na parada cardíaca, incluindo predição, reconhecimento, suporte durante a parada cardiorrespiratória, prognóstico, e risco de estratificação cardiovascular. Foram realizadas buscas nas bases de dados PubMed/MEDLINE, Google Scholar, EMBASE, Scopus, IEEE Xplore e ScienceDirect para estudos publicados de janeiro de 2000 a junho de 2025. Estudos que abordavam IA, aprendizado de máquina (machine learning) ou aprendizado profundo (deep learning) em contextos relacionados à parada cardíaca foram sintetizados descritivamente de acordo com a aplicação clínica, metodologia de IA e cenário de assistência. No total, 59 estudos foram incluídos. Seis categorias de aplicação foram identificadas: predição precoce de parada cardíaca ou deterioração clínica (n = 16); reconhecimento de parada cardíaca e ativação da resposta de emergência (n = 3); RCP intra-parada e suporte à desfibrilação (n = 6); determinação do prognóstico pós-parada cardíaca (n = 20); estratificação de risco para morte súbita cardíaca e arritmias malignas (n = 11); e modelos prognósticos cardiovasculares ou perioperatórios relacionados (n = 3). Abordagens baseadas em aprendizado profundo e redes neurais foram as metodologias mais frequentes (n = 35), seguidas por aprendizado de máquina tradicional (n = 18) e processamento de linguagem natural (n = 6). A IA mostrou-se particularmente promissora para predição baseada em ECG, trajetórias clínicas temporais, interpretação de chamadas de emergência, análises de forma de onda e desfibrilação, e prognóstico de mortalidade ou neurológico pós-parada. A IA apresenta grande potencial para apoiar as diversas etapas do cuidado na parada cardíaca, fornecendo ferramentas preditivas e de suporte à decisão. No entanto, as evidências atuais permanecem heterogêneas, uma vez que a maioria dos estudos depende de conjuntos de dados retrospectivos, populações selecionadas e validação externa ou prospectiva limitada.

Palavras-chave

Inteligência artificial; Ressuscitação cardiopulmonar; Sistemas de apoio à decisão clínica; Serviços médicos de emergência; Parada cardíaca; Aprendizado de máquina

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Submitted date:
01/09/2026

Accepted date:
07/05/2026

6ab5868ca9539532d70224f3 rba Articles
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