Brazilian Journal of Anesthesiology
https://app.periodikos.com.br/journal/rba/article/doi/10.1016/j.bjane.2025.844712
Brazilian Journal of Anesthesiology
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Association between troponin and NT-proBNP levels, cytokines, and clinical outcomes in early sepsis response: a cohort study

Wagner Nedel, Luis Valmor Portela

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Referências

1. Chauin A. The Main Causes and Mechanisms of Increase in Cardiac Troponin Concentrations Other Than Acute Myocardial Infarction (Part 1): Physical Exertion, Inflammatory Heart Disease, Pulmonary Embolism. Renal Failure, Sepsis. Vasc Health Risk Manag. 2021;17:601−17.

2. Cao C, Yu M, Chai Y. Pathological alteration and therapeutic implications of sepsis-induced immune cell apoptosis. Cell Death Dis. 2019;10:782.

3. Song J, Park DW, Moon S, Cho HJ, Park JH, Seok H, et al. Diagnostic and prognostic value of interleukin-6, pentraxin 3, and procalcitonin levels among sepsis and septic shock patients: a prospective controlled study according to the Sepsis-3 definitions. BMC Infect Dis. 2019;19:968.

4. Ryoo SM, Han KS, Ahn S, Shin TG, Hwang SY, Chung SP, et al. The usefulness of C-reactive protein and procalcitonin to predict prognosis in septic shock patients: A multicenter prospective registry-based observational study. Sci Rep. 2019;9:6579.

5. Zhang H, Liu D. Sepsis-related cardiomyopathy: Not an easy task for ICU physicians. Journal of Intensive Medicine. 2022; 2:257−9.

6. Nedel WL, Kopczynski A, Rodolphi MS, et al. Mortality of septic shock patients is associated with impaired mitochondrial oxidative coupling efficiency in lymphocytes: a prospective cohort study. Intensive Care Med Exp. 2021;9:39.

7. Evans L, Rhodes A, Alhazzani W, et al. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021. Intensive Care Med. 2021;47:1181−247.

8. Choi E, Nam H, Chung CR, et al. Impact of Elevated Troponin Level at the Time of Sepsis Recognition on the Clinical Outcomes: A Propensity Score-Matched Cohort Study. JAHA. 2025;14:e038651.

9. Lambden S, Laterre PF, Levy MM, Francois B. The SOFA score ‒ development, utility and challenges of accurate assessment in clinical trials. Crit Care. 2019;23:374.

10. Akbas T. Elevated Cardiac Troponin Levels as a Predictor of Increased Mortality Risk in Non-Cardiac Critically Ill Patients Admitted to a Medical Intensive Care Unit. J Clin Med. 2024;13:6025.


Submetido em:
16/07/2025

Aceito em:
11/11/2025

6977c71ba9539565282af41a rba Articles
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Braz J Anesthesiol

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