Combination of clonidine-bupivacaine in caudal epidural anesthesia for hypospadias surgery in children: prospective, randomized, blind study
Associação clonidina-bupivacaína na anestesia peridural caudal para cirurgia de hipospádia em crianças: estudo prospectivo, randomizado, encoberto
Ana Cláudia Mota Bonisson; Magda Lourenço Fernandes; Guilherme Freitas Araújo; Fabrício Eduardo Vieira; Luíza Melo Noronha; Renato Santiago Gomez
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References
Morton NS. Pain assessment in children. Paediatr Anaesth. 1997;4:26772.
Tsui BC, Berde CB. Caudal analgesia and anesthesia techniques in children. Curr Opin Anaesthesiol. 2005;18:283-8.
Wolf AR, Valley RD, Fear DW. Bupivacaine for caudal analgesia in infants and children: The optimal effective concentration. Anesthesiology. 1988;69:102-6.
Fernandes ML, Pires KCC, Tibúrcio MA. Caudal bupivacaine supplemented with morphine or clonidine, or supplemented with morphine plus clonidine in children undergoing infra-umbilical urological and genital procedures: a prospective, randomized and double-blind study. J Anesth. 2011;26:213-8.
De Beer DA, Thomas ML. Caudal additives in children - solutions or problems?. Br J Anaesth. 2003;90:487-98.
Schnabel A, Poepping DM, Pogatzki-Zahn EM. Efficacy and safety of clonidine as additive for caudal regional anesthesia: a quantitative systematic review of randomized controlled trials. Paediatr Anaesth. 2011;21:1219-30.
OF A.S. ASA New classification of physical status. Anesthesiology. 1963;24:111.
Ramsay MA, Savege TM, Simpson BR. Controlled sedation with alphaxalone-alphadolone. Br Med J. 1974;2:656-9.
Merkel SI, Shayevitz J. The FLACC: a behavioral scale for scoring postoperative pain in young children. Pediatr Nurs. 1997;23:293-7.
Feestini F, Dini D, Neri C. Control of postoperative pain in children undergoing hypospadias surgery: quasi-experimental controlled trial. Assist Inferm Ric. 2008;27:197-201.
Sanwatsarkar S, Kapur S, Khan N. Comparative study of caudal clonidine and midazolam added to bupivacaine during infra-umbilical surgeries in children. J Anaesthesiol Clin Pharmacol. 2017:3324-47.
Hong JY, Han SW, Kim WO. Effect of dexamethasone in combination with caudal analgesia on postoperative pain control in day-case paediatric orchiopexy. Br J Anaesth. 2010;105:506-10.
Klimscha W, Chiari A, Michalek-Sauberer A. The efficacy and safety of a clonidine/bupivacaine combination in caudal blockade for pediatric hernia repair. Anesth Analg. 1998;86:54-61.
Yildiz TS, Korkmaz F, Solak M. Clonidine addition prolongs the duration of caudal analgesia. Acta Anaesthesiol Scand. 2006;50:501-4.
Sharpe P, Klein JR, Thompson JP. Analgesia for circumcision in a paediatric population: comparison of caudal bupivacaine alone with bupivacaine plus two doses of clonidine. Paediatr Anaesth. 2001;11:695-700.
Priolkar S, D'Souza SA. Efficacy and safety of clonidine as an adjuvant to bupivacaine for caudal analgesia in paediatric infra-umbilical surgeries. J Clin Diagn Res. 2016;10:UC13-6.
De May JC, Strobet J, Poelaert J. The influence of sufentanil and/or clonidine on the duration of analgesia after caudal block for hypospadias repair surgery in children. Eur J Anaesthesiol. 2000;17:379-82.
Hansen TG, Henneberg SW, Walther-Larsen S. Caudal bupivacaine supplemented with caudal or intravenous clonidine in children undergoing hypospadias repair: a double-blind study. Br J Anaesth. 2004;92:223-7.
Luz G, Innerhofer P, Oswald E. Comparison of clonidine 1 microgram kg-1 with morphine 30 micrograms kg-1 for post-operative caudal analgesia in children. Eur J Anaesthesiol. 1999;16:42-6.
Taicher BM, Routh JC, Eck JB. The association between caudal anesthesia and increased risk of postoperative surgical complications in boys undergoing hypospadias repair. Paediatr Anaesth. 2017;27:688-94.