Castor polyurethane used as osteosynthesis plates: microstructural and thermal analysis
Moura Neto, Francisco Norberto de; Fialho, Ana Cristina Vasconcelos; Moura, Walter Leal de; Rosa, Adriana Gadelha Ferreira; Matos, José Milton Elias de; Reis, Fernando da Silva; Mendes, Milton Thélio de Albuquerque; Sales, Elton Santos Dias
Abstract
Bone fractures to be corrected need stabilization of their extremities, which is achieved with the use of plates and screws. This research aimed to produce castor bean polyurethane (Ricinus communis), to make resorbable plate, structural and thermal analysis. The production was made by the glycerolysis of the triglycerides present in the oil, after addition of polyol/glycerol and hexamethylene diisocyanate (HDI) to form urethane structures, with and without addition of hydroxyapatite. The characterization was by FTIR spectroscopy, scanning electron microscopy (SEM), X-ray diffraction, differential scanning calorimetry and thermogravimetry. Plates with dimensions of 40 mm X 10 mm X 2 mm were obtained. The SEM showed flat and homogeneous surface. DRX analysis showed the semi-crystallinity of the biomaterial. Glass transition and thermal stability up to 50 °C were observed, followed by thermal decomposition up to 450 °C. The produced polyurethane showed it is possible to be applied in the manufacture of plate.
Keywords
References
1 Morita, A. T., Toma, M. S., & de Paoli, M.-A. (2005). Módulo de reometria capilar e auto-reforçamento de baixo custo. Polímeros: Ciência e Tecnologia, 15(1), 68-72. http://dx.doi.org/10.1590/S0104-14282005000100015.
2 Kang, I. G., Jung, J. H., Kim, S. T., Choi, J. Y., & Sykes, J. M. (2014). Comparison of Tiatium and Biodegradable Plates for Treating Midfacial Fractures. Journal of Oral and Maxillofacial Surgery, 72(4), 762.e1-762.e4. http://dx.doi.org/10.1016/j.joms.2013.12.020.
3 Milori, F. P., Quitzan, J., Souza, R. S., Cirio, S. M., Dornbusch, P. T., & Prado, A. M. R. B. (2013). Placas ósseas confeccionadas a partir de diáfise cortical equina na osteossíntese femoral em coelho. Pesquisa Veterinária Brasileira, 33(10), 1201-1207. http://dx.doi.org/10.1590/S0100-736X2013001000005.
4 Park, Y. W. (2015). Bioabsorbable osteofixation for orthognathic surgery. Maxillofacial Plastic and Reconstructive Surgery, 37(1), 6. https://doi.org/10.1186/s40902-015-0003-7. PMid:25722967.
5 Erbetta, C. D. C., Viegas, C. C. B., Freitas, R. F. S., & Sousa, R. G. (2011). Síntese e caracterização térmica e química do copolímero poli(D,L-lactídeo-co-glicolídeo). Polímeros: Ciência e Tecnologia, 21(5), 376-382. http://dx.doi.org/10.1590/S0104-14282011005000063.
6 Nacer, R. S., Silva, B. A. K., Poppi, R. R., Silva, D. K. M., Cardoso, V. S., Delben, J. R. J., & Delben, A. A. S. T. (2015). Biocompatibility and osteogenesis of the castor bean polymer doped with silica (SiO2) or barium titanate (BaTiO3) nanoparticles. Acta Cirurgica Brasileira, 30(4), 255-263. http://dx.doi.org/10.1590/S0102-865020150040000004. PMid:25923258.
7 Merlini, C., Soldi, V., & Barra, G. M. O. (2011). Influence of fiber surface treatment and length on physico-chemical properties of short random banana fiber-reinforced castor oil polyurethane composites. Polymer Testing, 30(8), 833-840. http://dx.doi.org/10.1016/j.polymertesting.2011.08.008.
8 Marinho, N. P., Nascimento, E. M., Nisgoski, S., Magalhães, W. L. E., Neto, S. C., & Azevedo, E. C. (2013). Caracterização física e térmica de compósito de poliuretano derivado de óleo de mamona associado com partículas de bambu. Polímeros Ciência e Tecnologia, 23(2), 201-205.
9 Pradhan, K. C., & Nayak, P. L. (2012). Synthesis and characterization of polyurethane nanocomposite from castor oil- hexamethylene diisocyanate (HMDI). Advances in Applied Science Research, 3(5), 3045-3052. Retrieved in 2018, June 20, from: http://www.imedpub.com/articles/synthesis-and-characterization-of-polyurethane-nanocomposite-from-castoroil-hexamethylene-diisocyanate-hmdi.pdf
10 Patel, V. R., Dumancas, G. G., Viswanath, L. C. K., Maples, R., & Subong, B. J. (2016). Castor oil: properties, uses, and optimization of processing parameters in commercial production. Lipid Insights, 9(1), 1-12. http://dx.doi.org/10.4137/LPI.S40233. PMid:27656091.
11 Graça, Y. L. S. S., Opolski, A. C., Barboza, B. E. G., Erbano, B. O., Mazzaro, C. C., Klostermann, F. C., Sucharski, E. E., & Kubrusly, L. F. (2014). Biocompatibility of Ricinus communis polymer with addition of calcium carbonate compared to titanium. Experimental study in guinea pigs. Revista Brasileira de Cirurgia Cardiovascular; Orgao Oficial da Sociedade Brasileira de Cirurgia Cardiovascular, 29(2), 272-278. PMid:25140479.
12 Santos, V. T., Facco, G. G., Ortiz, H. C., & Silva, I. S. (2017). Behavior study of the doped castor bean polymer rod with bioactive glass and hidroxyapatite in mice fêmur medullary canal. Acta Cirurgica Brasileira, 32(2), 116-124. http://dx.doi.org/10.1590/s0102-865020170204. PMid:28300879.
13 Król, P. (2007). Synthesis methods, chemical structures and phase structures of linear polyurethanes. Properties and applications of linear polyurethanes in polyurethane elastomers, copolymers and ionomers. Progress in Materials Science, 52(6), 915-1015. http://dx.doi.org/10.1016/j.pmatsci.2006.11.001.
14 Dave, V., & Patel, H. S. (2017). Synthesis and characterization of interpenetrating polymer networks from transesterified castor oil based polyurethane and polystyrene. Journal of Saudi Chemical Society, 21(1), 18-24. http://dx.doi.org/10.1016/j.jscs.2013.08.001.
15 Sathiskumar, P. S., & Madras, G. (2011). Synthesis, characterization, degradation of biodegradable castor oil based polyesters. Polymer Degradation & Stability, 96(1), 1695-1704. http://dx.doi.org/10.1016/j.polymdegradstab.2011.07.002.
16 Zhang, L., Zhang, M., Hu, L., & Zhou, Y. (2014). Synthesis of rigid polyurethane foams with castor oil-based flame retardant polyols. Industrial Crops and Products, 52(1), 380-388. http://dx.doi.org/10.1016/j.indcrop.2013.10.043.
17 Lin, S., Huang, J., Chang, P. R., Wei, S., Xu, Y., & Zhang, Q. (2013). Structure and mechanical properties of new biomass-based nanocomposite: castor oil-based polyurethane reinforced with acetylated cellulose nanocrystal. Carbohydrate Polymers, 95(1), 91-99. http://dx.doi.org/10.1016/j.carbpol.2013.02.023. PMid:23618244.
18 Hejna, A., Kirpluks, M., Kosmela, P., Cabulis, U., Haponiuk, J., & Piszczyk, Ł. (2017). The influence of crude glycerol and castor oil-based polyol on thestructure and performance of rigid polyurethane-polyisocyanurate foams. Industrial Crops and Products, 95(1), 113-125. http://dx.doi.org/10.1016/j.indcrop.2016.10.023.
19 Mutlu, H., & Meier, M. A. R. (2010). Castor oil as a renewable resource for the chemical industry. European Journal of Lipid Science and Technology, 112(1), 10-30. http://dx.doi.org/10.1002/ejlt.200900138.
20 Monteiro, A. S. F., Macedo, L. G. S., Macedo, N. L., & Balducci, I. (2010). Polyurethane and PTFE membranes for guided bone regeneration: histopathological and ultrastructural evaluation. Medicina Oral, Patologia Oral y Cirugia Bucal, 15(2), e401-406. http://dx.doi.org/10.4317/medoral.15.e401. PMid:19767699.
21 Marano, R., & Tincani, A. J. (2016). Is there an ideal implant for orbital reconstructions? Prospective 64-case study. Journal of Cranio-Maxillo-Facial Surgery, 44(10), 1682-1688. http://dx.doi.org/10.1016/j.jcms.2016.08.006. PMid:27637477.
22 Costa, A. C. F. M., Lima, M. G., Lima, L. H. M. A., Cordeiro, V. V., Viana, K. M. S., Souza, C. V., & Lira, H. L. (2009). Hidroxiapatita: obtenção, caracterização e aplicações. Revista Eletrônica de Materiais e Processos, 4(3), 29-38.
23 Sheikh, F. A., Kanjwal, M. A., Macossay, J., Barakat, N. A. M., & Kim, H. Y. (2012). A simple approach for synthesis, characterization and bioactivity for bovine bones to fabricate the polyurethane nanofiber containing hydroxyapatite nanoparticle. Express Polymer Letters, 6(1), 1-22. http://dx.doi.org/10.3144/expresspolymlett.2012.5. PMid:24416082.
24 Potter, J. K., Malmquist, M., & Ellis, E. 3rd (2012). Biomaterials for reconstruction of the internal orbit. Oral and Maxillofacial Surgery Clinics of North America, 24(4), 609-627. http://dx.doi.org/10.1016/j.coms.2012.07.002. PMid:23107429.
25 Alves, E. G. L., Rezende, C. M. F., Oliveira, H. P., Borges, N. F., Mantovani, P. F., & Lara, J. S. (2010). Avaliação mecânica da placa de compósito de poli-hidroxibutirato e hidroxiapatita em modelos ósseos de gato. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 62(6), 1367-1374. http://dx.doi.org/10.1590/S0102-09352010000600011.
26 Cangemi, J. M., Santos, A. M., Claro Neto, S., & Chierice, G. O. (2008). Biodegradation of polyurethane derived from castor oil. Polímeros, 18(3), 201-206. http://dx.doi.org/10.1590/S0104-14282008000300004.
27 Callister, W. D. Jr. (2002). Ciência e engenharia de materiais: uma introdução. Rio de Janeiro: LTC.
28 Dubois, L., Steenen, S. A., Gooris, P. J. J., Bos, R. R. M., & Becking, A. G. (2016). Controversies in orbital reconstruction-III. Biomaterials for orbital reconstruction: a review with clinical recommendations. International Journal of Oral and Maxillofacial Surgery, 45(1), 41-50. http://dx.doi.org/10.1016/j.ijom.2015.06.024. PMid:26250602.
29 Stanton, D. C., Liu, F., Yu, J. W., & Mistretta, M. C. (2014). Use of bioresorbable plating systems in paediatric mandible fractures. Journal of Cranio-Maxillo-Facial Surgery, 42(7), 1305-1309. http://dx.doi.org/10.1016/j.jcms.2014.03.015. PMid:24815762.
30 Al-Moraissi, E. A., & Ellis, E. 3rd (2015). Biodegradable and titanium osteosynthesis provide similar stability for orthognathic surgery. Journal of Oral and Maxillofacial Surgery, 73(9), 1795-1808. http://dx.doi.org/10.1016/j.joms.2015.01.035. PMid:25864125.
31 Reis, E. C. C., Borges, A. P. B., Oliveira, P. M., Bicalho, S. M. C. M., Reis, A. M., & Silva, C. L. (2012). Desenvolvimento e caracterização de membranas rígidas, osteocondutoras e reabsorvíveis de polihidroxibutirato e hidroxiapatita para regeneração periodontal. Polímeros: Ciência e Tecnologia, 22(1), 73-79. http://dx.doi.org/10.1590/S0104-14282012005000007.
32 Kanno, T., Sukegawa, S., Furuki, Y., Nariai, Y., & Sekine, J. (2018). Overview of innovative advances in bioresorbable plate systems for oral and maxillofacial surgery. Japanese Dental Science Review, 54(3), 127-138. http://dx.doi.org/10.1016/j.jdsr.2018.03.003. PMid:30128060.