Mediterranean Journal of Pharmacy and Pharmaceutical Sciences
https://app.periodikos.com.br/journal/medjpps/article/doi/10.5281/zenodo.5171324

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences

Original article

Assessment of drug prescribing pattern and prescription errors in elderly patients 

Majda A. El yamani, Fathi M. Sherif

Downloads: 0
Views: 231

Abstract

The rate of aging is rapidly increasing and the term of geriatric refers to offer a medical care to elderly people. Drug consumption study on geriatric population is a vital issue since this group is totally neglected in Libya. The aim of this study was to assess drug utilization pattern among elderly patients in terms of world health organization core prescribing indicators and to evaluate the treatment cost. A total of 106 prescriptions were randomly collected from different community pharmacies located in Tripoli during the summer 2019, and were evaluated (total number of prescribed drugs is 359) for their clinical efficacy and safety. The findings revealed that 60 drugs acting on GIT (16.7%), 50 antimicrobial drugs (13.9%), 31 antihypertensive drugs (8.6%) and 30 drugs for respiratory diseases (8.4%) were prescribed to patients who are 65 years old or more. With regard to disease pattern in the elderly Libyan patients, 27 drugs were prescribed for diabetes mellitus (7.5%), 24 drugs for cardiovascular drugs (6.7%) and 14 drugs for anti-hyperlipidemia (3.9%). According to the WHO core drug use indicator pattern, the average number of drugs prescribed per encounter was 3.3. Prescription by generic name was low (41.5%). Antibiotics were 36.8% while injections were 26.6%. Thus, this study suggest that geriatric medicine and rational drug use should strongly be implanted in medical schools and teaching hospitals. Besides, a drug pattern use of the Libyan community is urgently required to avoid drug prescribing errors.

Keywords

Drug, elderly, geriatric, pharmacy, Libya, rational or irrational drug use 

References

1. World Health Organization (2003) Introduction to Drug Utilization Research Geneva: World Health Organization. https://apps.who.int/iris/handle/10665/42627.
2. Hogerzeil HV, Walker GJA, Sallami AO, Fernando G (1989) Impact of an essential drugs program on availability and rational use of drugs. Lancet. 1(8630):141-142.
3. Mamo DB, Alemu BK (2020) Rational drug-use evaluation based on world health organization core drug-use indicators in a tertiary referral hospital, northeast Ethiopia: a cross-sectional study. Drug, Healthcare and Patient Safety. 12: 15-21. DOI:10.2147/DHPS.S237021.
4. Thawani V (2010) Rational use of medicines: achievements and challenges. Indian Journal of Pharmacology. 42(2): 63-64. DOI: 10.4103/0253-7613.64486.
5. Abraham F, Varughese G, Mathew JC, John PM, Sam KG (2015) Drug utilization pattern among geriatric patients in a tertiary care teaching hospital. Asian Journal of Pharmacology and Clinical Research. 8(6): 191-194.
6. Meena VK, Atray M, Agrawal A (2015) Evaluation of drug utilization pattern in indoor patients of medicine department at tertiary care teaching hospital in southern Rajasthan. International Journal of Pharmaceutical Sciences and Research. 2(5): 112-117.
7. https://en.wikipedia.org/wiki/Libya. Access on January 14, 2019.
8. Thomas M, Alexander B, Tony S, Andrei Z (1997) Guidelines for implementing drug utilization review programs in hospitals. Arlington, VA/ Moscow, Russia. https://vdocument.in/guidelines-for-implementing-drug-utilization-review-programs.html. access on June 17, 2021.
9. Gautam CS, Aditya S (2006) Irrational Drug Combinations: Need to Sensitize Undergraduates, Pharmacology. 38(3): 169-170.
10. Al-Ghanim SA (2010) Profiling elderly and younger patients attending health care facilities: implications for health care planning. Journal of King Abdulaziz University: Economics and Administration. 24(2): 243-270. DOI:10.4197/ECO.24-2.6.
11. Swapna R, Nayaka B, Rajeshwari TV, Venkatadri (2015) Drug utilization pattern in geriatric inpatients of medicine department in a tertiary care teaching hospital. International Journal of Basic and Clinical Pharmacology. 4(3): 568-573.
12. Ramanath KV, Chaudhary S (2016) Study on pharmaceutical care in geriatrics of a rural tertiary care hospital. Research Journal of Pharmaceutical, Biological and Chemical Sciences. 7(4):1568-1578.
13. Pradhan S, Panda A, Panigrahy SR (2016) Analysis of drug utilization pattern in elderly in an outpatient department using who indicators: a cross sectional study. Research Journal of
Pharmaceutical, Biological and Chemical Sciences. 7(6): 2628-2633.
14. Swathi B, Bhavika (2016) Pattern of medication use among elderly patients attending medicine department in a tertiary care hospital in India. Asian Journal of Pharmacology and Clinical Research. 9(6): 266-269.
15. Sharma N, Advani U, kulshreshtha S, Parakh R, Bansal A, Sinha RR (2013) Screening of prescriptions in geriatric population in a tertiary care teaching hospital in north India. The Journal of Phytopharmacology. 2(5): 38-45.
16. Sultan HA, Sayegh KY, Mohammad AV, et al. (2015) Prescribing pattern of drugs in the geriatric patients in Jazan province, KSA. Pharmacy and Pharmacology International Journal. 2(1): 10-13.
17. John NN, Kumar AN (2013) A study on polypharmacy in senior Indian population. International Journal of Pharmaceutical, Chemical and Biological Sciences. 3(1): 168-171.
18. Mittal N, Mittal R, Singh I, Shafiq N, Malhotra S (2014) Drug utilization study in a tertiary care center: recommendations for improving hospital drug dispensing policies. Indian Journal of Pharmaceutical Sciences. 76(4): 308-314.
19. Geetha S, Sathisha Aithal, Balaji V, Swetha ES (2015) Analysis of drug utilization pattern among hypertensive patients admitted to medical intensive care unit of a tertiary care hospital. World Journal of Pharmaceutical Research. 4(3): 1320-130.
20. Lourdu Jafrin A, Venkata Naveen Kumar P, Udhayalakshmi T, Jayapriya B, Maruti (2013) Drug utilization patterns of geriatric patients admitted in the medicine department of a tertiary care hospital. International Journal of Pharmacy and Life Science. 4(11): 3087-3092.
21. Sapkota S, Pudasaini N, Singh C, Sagar GC (2011) Drug prescribing pattern and prescription errors in elderly: a retrospective study of inpatient records. Asian Journal of Phrenology and Clinical Research. 4(3): 129-132.
22. Veena DR, Padma L, Patil S (2012) Drug prescribing pattern in elderly patients in a teaching Hospital. Journal of Dental and Medical Sciences. 1(5): 39-42.
23. Joshi MP, Sugimoto T, Santoso B (1997) Geriatric prescribing in the medical wards of a teaching hospital in Nepal. Pharmaco-epidemiology Drug Safety. 6(6): 417-421.
24. Babar HS, Hussain S, Maqsood Z, Dad HA, Khan M, Rahman AA, Bukhsh A (2014) Adherence to prescription format and compliance with who core prescribing indicators. Journal of Pharm. Science and Research. 6(4): 195-199.
25. American Geriatrics Society updated (2012) Beers criteria for potentially inappropriate medication use in older adults. Journal of American Geriatric Society. 4, 60(4): 616-631. 26. The 2019 American Geriatrics Society (AGS) Beers Criteria® Update Expert Panel (2019). American Geriatrics Society 2019 Updated AGS Beers Criteria® for potentially inappropriate medication use in older adults. Journal of the American Geriatrics Society, 00(00), 1-21. doi: 10.1111/jgs.15767.
27. Zaveri HG, Mansuri SM, Patel VJ (2010) Use of potentially inappropriate medicines in elderly: a prospective study in medicine out-patient department of tertiary care teaching hospital. Indian Journal of Pharmacology. 42(2): 95-98.
28. Shah RB, Gajjar BM, Desai SV (2011) Evaluation of appropriateness of prescribing in geriatric patients using Beers criteria & Phadke's criteria and comparison thereof. Journal of Pharmacology and Pharmacotherapeutics. 2(4): 248-252.
29. Niwata S, Yamada Y, Ikegami N (2006) Prevalence of Inappropriate Medication using Beers Criteria in Japanese Long Term Care Facilities. BMC Geriatrics. 6, 1. DOI: 10.1186/1471-2318-6-1.
30. Sherif FM (2008) An evaluation of the prescribing patterns of drugs in Libya. Jamahiriya Medical Journal. 8(3): 203-206.
31. Elfituri AA, Almoudy A, Jbouda W, Abuflaiga W, Sherif FM (2018) Liby's Pharmaceutical situation: a professional opinion. International journal of Academic Health and Medical Research. 2(10): 5-9.


Submitted date:
05/30/2021

Reviewed date:
06/10/2021

Accepted date:
06/14/2021

Publication date:
10/26/2023

653af84fa95395065954c886 medjpps Articles
Links & Downloads

Mediterr J Pharm Pharm Sci

Share this page
Page Sections