1 Brott TG, Howard G, Lal BK, et al. CREST-2 Investigators. Medical Management and Revascularization for Asymptomatic Carotid Stenosis. N Engl J Med. 2026;394(3):219-31. https://doi.org/10.1056/NEJMoa2508800. PMid:41269206.

2 Walker MD, Marler JR, Goldstein M, et al. Endarterectomy for asymptomatic carotid artery stenosis. JAMA. 1995;273(18):1421-8. https://doi.org/10.1001/jama.1995.03520420037035. PMid:7723155.

3 Halliday A, Harrison M, Hayter E, et al. 10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): a multicentre randomised trial. Lancet. 2010;376(9746):1074-84. https://doi.org/10.1016/S0140-6736(10)61197-X. PMid:20870099.

4 Ristow AVB, Massière B, Meirelles GV, et al. Brazilian Angiology and Vascular Surgery Society Guidelines for the treatment of extracranial cerebrovascular disease. J Vasc Bras. 2024;23:e20230094. PMid:39099701.

5 Donners SJA, van Velzen TJ, Cheng SF, et al. Optimised medical therapy alone versus optimised medical therapy plus revascularisation for asymptomatic or low-to-intermediate risk symptomatic carotid stenosis (ECST-2): 2-year interim results of a multicentre randomised trial. Lancet Neurol. 2025;24(5):389-99. https://doi.org/10.1016/S1474-4422(25)00107-3. PMid:40252662.