Jornal Vascular Brasileiro
https://app.periodikos.com.br/journal/jvb/article/doi/10.1590/1677-5449.202300591
Jornal Vascular Brasileiro
Diretriz

Diretrizes sobre doença arterial periférica da Sociedade Brasileira de Angiologia e Cirurgia Vascular

Brazilian Society of Angiology and Vascular Surgery guidelines on peripheral artery disease

Fabiano Luiz Erzinger; Afonso César Polimanti; Daniel Mendes Pinto; Gustavo Murta; Marcus Vinicius Cury; Ricardo Bernardo da Silva; Rodrigo Bruno Biagioni; Sergio Quilici Belckzac; Edwaldo Edner Joviliano; Walter Junior Boin de Araujo; Julio Cesar Peclat de Oliveira

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Resumo

Pacientes com doença arterial periférica e aterosclerose generalizada apresentam alto risco de complicações cardiovasculares e nos membros, o que afeta sua qualidade de vida e longevidade. A doença aterosclerótica das extremidades inferiores está associada à alta morbimortalidade cardiovascular, sendo necessário para sua adequada terapia realizar o tratamento dos fatores dependentes do paciente, como a modificação no estilo de vida, e dos fatores dependentes do médico, como o tratamento clínico, tratamento endovascular ou cirurgia convencional. A abordagem médica para a doença arterial periférica é multifacetada, e inclui como principais medidas a redução do nível do colesterol, a terapia antitrombótica, o controle da pressão arterial e do diabetes e a cessação do tabagismo. A adesão a esse regime pode reduzir as complicações relacionadas aos membros, como a isquemia crônica que ameaça o membro e pode levar à sua amputação, e as complicações sistêmicas da aterosclerose, como o acidente vascular cerebral e infarto do miocárdio.

Palavras-chave

doença arterial periférica; diagnóstico; tratamento; metanálise

Abstract

Patients with peripheral artery disease and generalized atherosclerosis are at high risk of cardiovascular and limb complications, affecting both quality of life and longevity. Lower limb atherosclerotic disease is associated with high cardiovascular morbidity and mortality and adequate management is founded on treatments involving patient-dependent factors, such as lifestyle changes, and physician-dependent factors, such as clinical treatment, endovascular treatment, or conventional surgery. Medical management of peripheral artery disease is multifaceted, and its most important elements are reduction of cholesterol level, antithrombotic therapy, control of arterial blood pressure, control of diabetes, and smoking cessation. Adhesion to this regime can reduce complications related to the limbs, such as chronic limb-threatening ischemia, that can result in amputation, and the systemic complications of atherosclerosis, such as stroke and myocardial infarction.

Keywords

peripheral artery disease; diagnosis; treatment; metanalysis.

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