Evaluation of cardiovascular disease in patients with systemic arterial hypertension in relation to age and sex: a retrospective study in a south Indian population
Avaliação de doença cardiovascular em pacientes com hipertensão arterial sistêmica em relação a idade e sexo: estudo retrospectivo em uma população do sul da Índia
Ashwini Aithal Padur, Aisyah binti Hamdan, Talissa Tatiana binti Intisar Patrick Abdullah, Chandrigga Gunalan, Naveen Kumar
Abstract
Background: Systemic arterial hypertension manifests as constant elevation of blood pressure and is considered to be an important cardiovascular risk factor. Systemic evaluation of cardiovascular diseases in patients with systemic arterial hypertension is imperative for prevention. Objectives: The objective of the present study was to investigate and inter-relate sex and age with systemic arterial hypertension and cardiovascular diseases. Methods: Medical records of patients with systemic arterial hypertension and cardiovascular disease were evaluated. Data from the medical records were recorded in a prescribed protocol and the data were analyzed and correlated to the patients’ age and sex. Results: A total of 170 medical records for patients who visited the cardiology department were reviewed. Of these, 50 patients had systemic arterial hypertension and 19 of this subset had cardiovascular diseases. When we correlated systemic arterial hypertension with age, we observed that patients in the 51-60 years age group were more prone to systemic arterial hypertension (36%). Most of the patients with both systemic arterial hypertension and cardiovascular disease were female and in the 61-70 years age group, while among males the highest rate of occurrence was seen in the 51-60 years age group. The correlation coefficient (r) was 0.62, indicating a moderate, positive, linear relationship between systemic arterial hypertension and cardiovascular disease. Conclusions: A majority of patients with systemic arterial hypertension may develop cardiovascular disease and, as age increases, the tendency to develop hypertension also increases.
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Resumo
Contexto: A hipertensão arterial sistêmica se manifesta como elevação constante da pressão sanguínea e é considerada um importante fator de risco cardiovascular. A avaliação sistêmica de doenças cardiovasculares em pacientes com hipertensão arterial sistêmica é crucial para a prevenção. Objetivos: O objetivo deste estudo foi investigar e inter-relacionar sexo e idade com hipertensão arterial sistêmica e doença cardiovascular. Métodos: Prontuários médicos de pacientes com hipertensão arterial sistêmica e doença cardiovascular foram avaliados. Dados dos prontuários médicos foram lançados em um protocolo pré-definido, e os dados foram analisados e correlacionados com a idade e o sexo dos pacientes. Resultados: Um total de 170 prontuários de pacientes que visitaram o departamento de cardiologia foram revisados. Destes, 50 pacientes apresentavam hipertensão arterial sistêmica, e destes, 19 tinham doença cardiovascular. Ao correlacionar hipertensão arterial sistêmica com idade, observamos que pacientes do grupo etário de 51-60 anos estavam mais suscetíveis a apresentar hipertensão arterial sistêmica (36%). A maioria dos pacientes com hipertensão arterial sistêmica e doença cardiovascular era do sexo feminino e estava no grupo etário de 61-70 anos; já entre os pacientes do sexo masculino, a maior taxa de ocorrência foi no grupo etário de 51-60 anos. O coeficiente de correlação (r) foi 0,62, indicando uma relação moderada, positiva, linear entre hipertensão arterial sistêmica e doença cardiovascular. Conclusões: A maioria dos pacientes com hipertensão arterial sistêmica pode desenvolver doença cardiovascular; conforme a idade aumenta, também cresce a tendência a desenvolver hipertensão.
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References
1. Hall JE, Guyton AC. Guyton and Hall textbook of medical physiology. 12th ed. Philadelphia: Saunders Elsevier; 2011. 224 p.
2. Yusuf PS, Hawken S, Ôunpuu S, et al. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case control study. Lancet. 2004;364(9438):937-52. PMid:15364185. http://dx.doi.org/10.1016/S0140-6736(04)17018-9.
3. Okrainec K, Banerjee DK, Eisenberg MJ. Coronary artery disease in the developing world. Am Heart J. 2004;148(1):7-15. PMid:15215786. http://dx.doi.org/10.1016/j.ahj.2003.11.027.
4. Milane A, Abdallah J, Kanbar R, et al. Association of hypertension with coronary artery disease onset in the Lebanese population. Springerplus. 2014;3(1):533. PMid:25279324. http://dx.doi.org/10.1186/2193-1801-3-533.
5. Yusuf S, Reddy S, Ounpuu S, Anand S. Global burden of cardiovascular diseases: part II: variations in cardiovascular disease by specific ethnic groups and geographic regions and prevention strategies. Circulation. 2001;104(23):2855-64. PMid:11733407. http://dx.doi.org/10.1161/hc4701.099488.
6. Aggarwal A, Aggarwal S, Sharma V. Metabolic syndrome and coronary artery disease in Indians younger than 40 years. J Endocrinol Metab. 2012;2:39-45.
7. World Health Organization. The World Health Report 1999: making a difference. Geneva: World Health Organization; 1999.
8. Gupta R. Burden of coronary heart disease in India. Indian Heart J. 2005;57(6):632-8. PMid:16521628.
9. Joshi P, Islam S, Pais P, et al. Risk factors for early myocardial infarction in South Asians compared with individuals in other countries. JAMA. 2007;297(3):286-94. PMid:17227980. http://dx.doi.org/10.1001/jama.297.3.286.
10. Van den Hoogen PC, Seidell JC, Menotti A, Kromhout D. Blood pressure and long term coronary heart disease mortality in the Seven Countries Study: implications for clinical practice and public health. Eur Heart J. 2000;21(20):1639-42. PMid:11032686. http://dx.doi.org/10.1053/euhj.2000.2270.
11. Iqbal R, Ahmad Z, Malik F, et al. A statistical analysis of hypertension as cardiovascular risk factor. Middle East J Sci Res. 2012;12(1):19-22.
12. Blair DA, Glover WE, Greenfield AD, Roddie IC. Excitation cholinergic vasodilator nerves to human skeletal muscles during emotional stress. J Physiol. 1959;148(3):633-47. PMid:13801238. http://dx.doi.org/10.1113/jphysiol.1959.sp006312.
13. Aggarwal A, Aggarwal S, Goel A, Sharma V, Dwivedi S. A retrospective case control study of modifiable risk factors and cutaneous markers in Indian patients with young coronary artery disease. JRSM Cardiovasc Dis. 2012;1(3).
14. Kannel WB. Fifty years of framingham study contributions to understanding hypertension. J Hum Hypertens. 2000;14(2):83-90. PMid:10723112. http://dx.doi.org/10.1038/sj.jhh.1000949.
15. Levy D, Larson MG, Vasan RS, Kannel WB, Ho KK. The progression from hypertension to congestive heart failure. JAMA. 1996;275(20):1557-62. PMid:8622246. http://dx.doi.org/10.1001/jama.1996.03530440037034.
16. Fuster V, Pearson TA. 27th Betheseda Conference. Matching the intensity of risk factor management with the hazard of coronary heart disease events. J Am Coll Cardiol. 1996;27:957-1047. PMid:8609361.
17. Buttar HS, Li T, Ravi N. Prevention of cardiovascular diseases: role of exercise, dietary interventions, obesity and smoking cessation. Exp Clin Cardiol. 2005;10(4):229-49. PMid:19641674.
18. Prabhakaran P, Ajay VS, Prabhakaran D, et al. Global cardiovascular disease research survey. J Am Coll Cardiol. 2007;50(24):2322-8. PMid:18068042. http://dx.doi.org/10.1016/j.jacc.2007.08.040.
19. Bala A, Gupta BM. Mapping of Indian neuroscience research: a scientometric analysis of research output during 1999-2008. Neurol India. 2010;58(1):35-41. PMid:20228461. http://dx.doi.org/10.4103/0028-3886.60393.
20. Prabhakaran D, Yusuf S. Cardiovascular disease in India: lessons learnt & challenges ahead. Indian J Med Res. 2010;132(5):529-30. PMid:21150004.
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