Evidence-Based Data Regarding the Use of Antibiotic-loaded Cement in Hip Arthroplasty. A bibliometric analysis of 50 years
Datos basados en la evidencia sobre el uso de cemento con antibióticos en la artroplastia de cadera. Análisis blbliométrico de 50 años
Sebastian Alejandro Arias Tamayo, María Paula Lugo Pinilla, Andres Granados Zarate, José Daniel Cuastumal Martínez, Juan Felipe Casabon Pastrana, Jesus David Tipon Mayorga, Paula Alejandra Bernal Rojas, Cesar Mauricio Arango Ospina, Edwin Alejandro Gallego Gonzalez, Michael Ortega Sierra
Abstract
Introduction: The use of antibiotic-loaded cement is an intraoperative tool that has demonstrated potential benefits in hip arthroplasty. However, the global landscape of research on this topic remains unknown. The objective of this study was to analyze the scientific growth, characteristics, and metrics of global and historical research on the use of antibiotic-loaded cement in hip arthroplasty.
Material and methods: A cross-sectional bibliometric study was conducted using Scopus as the data source.
Results: A total of 523 documents published between 1973 and 2023 were selected. 89.9% (n=470) of the production consisted of original articles, with 11.85% being multi-center. 84.1% of the authors have published a single article, followed by 10.3% who have published two articles. Research has predominantly focused on adults or the elderly, with an emphasis on outcome evaluation (notably reoperation), assessing various antibiotic agents, and frequently employing retrospective designs.
Conclusions: There has been a sustained increase in research on the use of antibiotic-loaded cement in hip arthroplasty over the last 50 years. The research trend has shifted towards the evaluation of adult or elderly patients, exploration of antimicrobial agents, techniques, and health outcomes, primarily using observational and retrospective designs. An emerging research-focus is the study of hip arthroplasty in rheumatoid arthritis patients.
Keywords
Resumen
Introducción: El uso de cemento cargado con antibiótico, es una herramienta intraoperatoria que ha demostrado potenciales beneficios en la artroplastia de cadera. Sin embargo, se desconoce el panorama global de la investigación sobre este tópico. El objetivo de este estudio fue analizar el crecimiento científico, características y métricas de la investigación global e histórica sobre el uso de cemento cargado con antibiótico en artroplastia de cadera.
Material y métodos: Estudio bibliométrico de corte transversal, que utilizó como fuente de datos la base Scopus.
Resultados: Se seleccionaron 523 documentos publicados entre 1973 y 2023. El 89,9% (n=470) de la producción consistió en artículos originales, siendo el 11,85% multicéntricos. El 84,1% de los autores han publicado un único artículo, seguido de un 10,3% que han publicado dos artículos. La investigación se ha centrado predominantemente en adultos o ancianos, con énfasis en la evaluación de resultados (especialmente la reoperación), evaluando diversos agentes antibióticos y empleando con frecuencia diseños retrospectivos.
Conclusiones: En los últimos 50 años se ha producido un aumento sostenido de la investigación sobre el uso de cemento cargado con antibióticos en la artroplastia de cadera. La tendencia de la investigación se ha desplazado hacia la evaluación de pacientes adultos o ancianos, la exploración de los agentes antimicrobianos, las técnicas y los resultados sanitarios, utilizando principalmente diseños observacionales y retrospectivos. Un nuevo foco de investigación es el estudio de la artroplastia de cadera en pacientes con artritis reumatoide.
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References
1.Feng JN, Zhang CG, Li BH, Zhan SY, Wang SF, Song CL. Global burden of hip fracture: The Global Burden of Disease Study. Osteoporos Int. 2024;35(1):41-52. doi: 10.1007/s00198-023-06907-3.
2.Schattner A. The burden of hip fractures-why aren't we better at prevention? QJM. 2018;111(11):765-7. doi: 10.1093/qjmed/hcx216. PMID: 29165606.
3.Dong Y, Zhang Y, Song K, Kang H, Ye D, Li F. What was the Epidemiology and Global Burden of Disease of Hip Fractures From 1990 to 2019? Results From and Additional Analysis of the Global Burden of Disease Study 2019. Clin Orthop Relat Res. 2023;481(6):1209-20. doi: 10.1097/CORR.0000000000002465.
4.Masters J, Metcalfe D, Ha JS, Judge A, Costa ML. Surgical site infection after hip fracture surgery: a systematic review and meta-analysis of studies published in the UK. Bone Joint Res. 2020;9(9):554-62. doi: 10.1302/2046-3758.99.BJR-2020-0023.R1.
5.Szymski D, Walter N, Krull P, Melsheimer O, Lang S, Grimberg Aet al. The Prophylactic Effect of Single vs. Dual Antibiotic-Loaded Bone Cement against Periprosthetic Joint Infection Following Hip Arthroplasty for Femoral Neck Fracture: An Analysis of the German Arthroplasty Registry. Antibiotics (Basel). 2023;12(4):732. doi: 10.3390/antibiotics12040732.
6.Agni NR, Costa ML, Achten J, Peckham N, Dutton SJ, Png ME, et al. High-dose dual-antibiotic loaded cement for hip hemiarthroplasty in the UK (WHiTE 8): a randomised controlled trial. Lancet. 2023;402(10397):196-202. doi: 10.1016/S0140-6736(23)00962-5.
7.Bingham J. When and How Should I Use Antibiotic Cement in Primary and Revision Joint Arthroplasty? J Arthroplasty. 2022;37(8):1435-7. doi: 10.1016/j.arth.2022.02.001.
8.Lozada-Martinez ID, Visconti-Lopez FJ, Marrugo-Ortiz AC, Ealo-Cardona CI, Camacho-Pérez D, Picón-Jaimes YA. Research and Publication Trends in Pediatric Surgery in Latin America: A Bibliometric and Visual Analysis from 2012 to 2021. J Pediatr Surg. 2023;58(10):2012-9. doi: 10.1016/j.jpedsurg.2023.04.003.
9.Yubo S, Ramayah T, Hongmei L, Yifan Z, Wenhui W. Analysing the current status, hotspots, and future trends of technology management: Using the WoS and scopus database. Heliyon. 2023;9(9):e19922. doi: 10.1016/j.heliyon.2023.e19922.
10.10. Aria M, Cuccurullo C. Bibliometrix: An R-Tool for Comprehensive Science Mapping Analysis. J Informetr. 2017; 11:95-975. doi: 10.1016/j.joi.2017.08.007.
11.Rousseau R, Egghe L, Guns R. Becoming Metric-Wise: A Bibliometric Guide for Researchers. 1st ed. Belgium: Chandos Publishing; 2018.
12.Todeschini R, Baccini A. Handbook of Bibliometric Indicators: Quantitative Tools for Studying and Evaluating Research. 1st ed. Italy: Wiley-VCH Verlag GmbH & Co. KGaA; 2016. doi: 10.1002/9783527681969.
13.Buchholz HW, Elson RA, Engelbrecht E, Lodenkämper H, Röttger J, Siegel A. Management of deep infection of total hip replacement. J Bone Joint Surg Br. 1981;63-B(3):342-53. doi: 10.1302/0301-620X.63B3.7021561.
14.Engesaeter LB, Lie SA, Espehaug B, Furnes O, Vollset SE, Havelin LI. Antibiotic prophylaxis in total hip arthroplasty: effects of antibiotic prophylaxis systemically and in bone cement on the revision rate of 22,170 primary hip replacements followed 0-14 years in the Norwegian Arthroplasty Register. Acta Orthop Scand. 2003;74(6):644-51. doi: 10.1080/00016470310018135.
15.Masri BA, Duncan CP, Beauchamp CP. Long-term elution of antibiotics from bone-cement: an in vivo study using the prosthesis of antibiotic-loaded acrylic cement (PROSTALAC) system. J Arthroplasty. 1998;13(3):331-8. doi: 10.1016/s0883-5403(98)90179-6.
16.Greenhalgh T, Raftery J, Hanney S, Glover M. Research impact: a narrative review. BMC Med. 2016;14:78. doi: 10.1186/s12916-016-0620-8.
17.García Ancira C. [Evaluation of Scientific Impact Assessment in Educational Researches through a Case Study]. Rev Cuba Educ Super. 2022;41(2):523-33.
18.18. Cañedo-Andalia R, Cruz-Font J, Nodarse-Rodríguez M[. [Impact of Cuban’s Health Research Published in National Journals: are there reasons for urgent intervention?]. Rev Cuban Cardiol. 2015;21(2):1-7.
19.Vaudano E. Research Collaborations and Quality in Research: Foes or Friends? Handb Exp Pharmacol. 2020;257:383-98. doi: 10.1007/164_2019_293.
20.Anaya JM. The diagnosis and clinical significance of polyautoimmunity. Autoimmun Rev. 2014;13(4-5):423-6. doi: 10.1016/j.autrev.2014.01.049.
21.Lozada-Martinez ID, Bolaño-Romero MP, Picón-Jaimes YA, Moscote-Salazar LR, Narvaez-Rojas AR. Quality or quantity? Questions on the growth of global scientific production. Int J Surg. 2022;105:106862. doi: 10.1016/j.ijsu.2022.106862.
22.Lozada-Martinez ID, Suarez-Causado A, Solana-Tinoco JB. Ethnicity, genetic variants, risk factors and cholelithiasis: The need for eco-epidemiological studies and genomic analysis in Latin American surgery. Int J Surg. 2022;99:106589. doi: 10.1016/j.ijsu.2022.106589.
Submitted date:
11/27/2023
Reviewed date:
03/22/2024
Accepted date:
03/31/2024
Publication date:
04/01/2024