Sexual function, depressive symptoms and quality of life of people undergoing hemodialysis therapy
Función sexual, síntomas depresivos y calidad de vida de las personas en tratamiento de hemodiálisis
Função sexual, sintomatologia depressiva e qualidade de vida de pessoas submetidas à terapia hemodialítica
Diego Pires Cruz; Edison Vitório de Souza Júnior; Anderson Fábio Moura Weiber; Cristiane dos Santos Silva; Benedito Fernandes da Silva Filho; Anderson Jambeiro de Souza; Namie Okino Sawada
Abstract
Objective: to analyze the correlation between sexual function, depressive symptomatology and quality of life of people on hemodialysis treatment.
Method: a cross-sectional study developed with 54 participants. Data collection occurred between the months of March and May 2020. The data were analyzed with the Mann-Whitney and Spearman Correlation tests, with a 95% confidence interval.
Results: the correlation between sexual function and depressive symptomatology was only clinically relevant for women (ρ= -0.724). Regarding quality of life, it was observed that the overall sexual function of men is negatively correlated with the pain dimension (ρ= -0.349) and with the social function (ρ= -0.347). For women, overall sexual function is positively correlated with physical function (ρ= 0.501), general health (ρ= 0.737), mental component (ρ= 0.497), sleep (ρ= 0.753), quality of social interaction (ρ= 0.621), and patient satisfaction (ρ= 0.457).
Conclusion and implications for the practice: increased sexual function was strongly correlated with reduced depressive symptoms and increased quality of life, implying the need to strengthen sexual approaches through protocols that provide referral flows to specialized trans-disciplinary teams.
Keywords
Resumen
Palabras clave
Resumo
Objetivo: analisar a correlação entre função sexual, sintomatologia depressiva e qualidade de vida de pessoas em tratamento hemodialítico.
Método: estudo transversal desenvolvido com 54 participantes. A coleta de dados ocorreu entre os meses de março a maio de 2020. Os dados foram analisados com os testes de Mann-Whitney e Correlação de Spearman, com intervalo de confiança de 95%.
Resultados: a correlação entre a função sexual e a sintomatologia depressiva somente foi clinicamente relevante para as mulheres (ρ= -0,724). Já em relação à qualidade de vida, observou-se que a função sexual geral dos homens está negativamente correlacionada com a dimensão dor (ρ= -0,349) e com a função social (ρ= -0,347). Já para as mulheres, a função sexual geral está positivamente correlacionada com a função física (ρ= 0,501), saúde geral (ρ= 0,737), componente mental (ρ= 0,497), sono (ρ= 0,753), qualidade da interação social (ρ= 0,621) e com a satisfação do paciente (ρ= 0,457).
Conclusão e implicações para a prática: o aumento da função sexual esteve fortemente correlacionado com a redução de sintomatologia depressiva e com o aumento da qualidade de vida, implicando a necessidade de fortalecer as abordagens sexuais por meio de protocolos que ofereçam fluxos de encaminhamento às equipes transdisciplinares especializadas.
Palavras-chave
References
1 Lessa SRO, Bezerra JNM, Barbosa SMC, Luz GOA, Borba AKOT. Prevalence and factors associated with the occurrence of adverse events in the hemodialysis service. Texto Contexto Enferm. 2018;27(3):e3830017.
2 Schmidt DB. Quality of life and mental health in hemodialysis patients: a challenge for multiprofessional practices. J Bras Nefrol. 2019;41(1):10-1.
3 Ganu VJ, Boima V, Adjei DN, Yendork JS, Dey ID, Yorke E et al. Depression and quality of life in patients on long term hemodialysis at a national hospital in Ghana: a cross-sectional study. Ghana Med J. 2018;52(1):22-8.
4 Yaqoob S, Yaseen M, Abdullah H, Jarullah FA, Khawaja UA. Sexual dysfunction and associated anxiety and depression in female hemodialysis patients: a cross-sectional study at Karachi Institute of Kidney Diseases. Cureus. 2020;12(8):e10148.
5 Guven S, Sari F, Inci A, Cetinkaya R. Sexual dysfunction is associated with depression and anxiety in patients with predialytic chronic kidney disease. Eurasian J Med. 2018;50(2):75-80.
6 Fugl-Meyer KS, Nilsson M, Hylander B, Lehtihet M. Sexual function and testosterone level in men with conservatively treated chronic kidney disease. Am J Mens Health. 2017;11(4):1069-76.
7 Pyrgidis N, Mykoniatis I, Tishukov M, Sokolakis I, Nigdelis MP, Sountoulides P et al. Sexual dysfunction in women with end-stage renal disease: a systematic review and meta-analysis. J Sex Med. 2021;18(5):936-45.
8 Pizzol D, Xiao T, Yang L, Demurtas J, McDermott D, Garolla A et al. Prevalence of erectile dysfunction in patients with chronic kidney disease: a systematic review and meta-analysis. Int J Impot Res. 2021;33(5):508-15.
9 van Ek GF, Gawi A, Nicolai MPJ, Krouwel EM, Den Oudsten BL, Den Ouden MEM et al. Sexual care for patients receiving dialysis: A cross-sectional study identifying the role of nurses working in the dialysis department. J Adv Nurs. 2018;74(1):128-36.
10 Tekkarismaz N, Tunel M, Ozer C. Dialysis modality and sexual dysfunction in male patients. Andrologia. 2020;52(10):e13735.
11 Neves PDMM, Sesso RCC, Thomé FS, Lugon JR, Nasicmento MM. Brazilian Dialysis Census: analysis of data from the 2009-2018 decade. J Bras Nefrol. 2020;42(2):191-200.
12 Abdo CHN. Elaboração e validação do quociente sexual - versão masculina, uma escala para avaliar a função sexual do homem. RBM Rev Bras Med. 2006;63(1/2):42-6.
13 Abdo CHN. Elaboração e validação do quociente sexual - versão feminina: uma escala para avaliar a função sexual da mulher. RBM Rev Bras Med. 2006;63(9):477-82.
14 Gorenstein C, Andrade L. Validation of a Portuguese version of the Beck Depression Inventory and the State-Trait Anxiety Inventory in Brazilian subjects. Braz J Med Biol Res. 1996;29(4):453-7. PMid:8736107.
15 Pretto CR, Rosa MBC, Dezordi CM, Benetti SAW, Colet CF, Stumm EMF. Depression and chronic renal patients on hemodialysis: associated factors. Rev Bras Enferm. 2020;73(Suppl 1):e20190167.
16 Duarte PS, Ciconelli RM, Sesso R. Cultural adaptation and validation of the “Kidney Disease and Quality of Life - Short Form (KDQOL-SFTM 1.3)” in Brazil. Braz J Med Biol Res. 2005;38(2):261-70.
17 Hulley SB, Cumming SR, Browner WS, Grady DG, Hearst NB, Newman TB. Delineando a pesquisa clínica: uma abordagem epidemiológica. 2a ed. Porto Alegre: Artmed; 2003.
18 Theofilou PA. Sexual functioning in chronic kidney disease: the association with depression and anxiety. Hemodial Int. 2012;16(1):76-81.
19 Pavone C, Di Fede AS, Mannone P, Tulone G, Bishqemi A, Abrate A et al. Sexual dysfunction in dialytic patients. A prospective cross-sectional observational study in two hemodialysis centers. Arch Ital Urol Androl. 2021;93(2):215-20.
20 Luo L, Xiao C, Xiang Q, Zhu Z, Liu Y, Wang J et al. Significant increase of sexual dysfunction in patients with renal failure receiving renal replacement therapy: a systematic review and meta-analysis. J Sex Med. 2020 dez;17(12):2382-93.
21 Chou J, Kiebalo T, Jagiello P, Pawlaczyk K. Multifaceted sexual dysfunction in dialyzing men and women: pathophysiology, diagnostics, and therapeutics. Life. 2021;11(4):311.
22 Gerogianni G, Kouzoupis A, Grapsa E. A holistic approach to factors affecting depression in haemodialysis patients. Int Urol Nephrol. 2018;50(8):1467-76.
23 Nasrallah YS, Marie REM, Eyada MMK. Female sexual function and depressive symptoms among premenopausal females on hemodialysis. Hum Androl. 2019;9(2):34-9.
24 Gomes ICC, Manzini CSS, Ottaviani AC, Moraes BIP, Lanzotti RB, Orlandi FS. Attitudes facing pain and the spirituality of chronic renal patients in hemodialysis. Br J Pain. 2018;1(4):320-4.
25 Pan D, Xu ZH, Gao Q, Li M, Guan Y, Zhao ST. Relationship between penile erection and the ratio of estradiol to testosterone: a retrospective study. Andrologia. 2020;52(9):e13701.
26 Gregg LP, Bossola M, Ostrosky-Frid M, Hedayati SS. Fatigue in CKD: epidemiology, pathophysiology, and treatment. Clin J Am Soc Nephrol. 2021;16(9):1445-55.
27 Mirghaed MT, Sepehrian R, Rakhshan A, Gorji H. Sleep quality in iranian hemodialysis patients: a systematic review and meta-analysis. Iran J Nurs Midwifery Res. 2019;24(6):403-9. https://doi.org/10.4103/ijnmr.IJNMR_184_18. PMID: 31772913.
28 Rehman IU, Chohan TA, Bukhsh A, Khan TM. Impact of pruritus on sleep quality of hemodialysis patients: a systematic review and meta-analysis. Medicina (Kaunas). 2019;55(10):699.
29 Costa FAP, Cavalcante MCV, Lamy ZC, Salgado N Fo. Cotidiano de portadores de doença renal crônica - percepções sobre a doença. Rev Médica Minas Gerais [Internet]. 2009 [citado 2021 dez 21];19(4 Supl 2):S12-7. Disponível em:
30 Sitjar-Suñer M, Suñer-Soler R, Masià-Plana A, Chirveches-Pérez E, Bertran-Noguer C, Fuentes-Pumarola C. Quality of life and social support of people on peritoneal dialysis: mixed methods research. Int J Environ Res Public Health. 2020;17(12):4240.
Submitted date:
01/11/2022
Accepted date:
05/09/2022
Facebook
Google+
Twitter
LinkedIn
Mendeley
StumbleUpon
CiteULike
Reddit
Email