Autopsy and Case Reports
https://app.periodikos.com.br/journal/autopsy/article/doi/10.4322/acr.2024.519
Autopsy and Case Reports
Clinical Case Report

Cytological diagnosis of hyaline-vascular type of Castleman disease

Deepa Rani; Anupam Varshney; Kanika Rastogi

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Abstract

Castleman disease (CD) is a rare, benign lymphoproliferative disorder, mostly involving the mediastinal lymph nodes, but can occur wherever lymphoid tissue is found. With only a few published case reports, there needs to be more literature on its cytological findings. We report the case of a 63-year-old female presenting with left upper cervical swelling. Fine needle aspiration cytology smears showed variably sized lymphoid follicles with diminished germinal centers, prominence of follicular dendritic cells, and capillaries traversing some of the follicles. The possibility of a hyaline-vascular type of Castleman disease was suggested. Histopathology confirmed the cytological diagnosis. The index case is being presented to discuss the cytological features of the CD along with its histological and immunohistochemical correlation.

Keywords

Hyaline-vascular, Castleman Disease, fine needle aspiration cytology

References

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Submitted date:
06/28/2024

Accepted date:
08/13/2024

Publication date:
09/27/2024

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