Hyaline cartilage at the portal plate and gallbladder in biliary atresia
Sangamitra Rajasekaran; Hari Neupane; Monika Bawa; Uma Nahar Saikia; Sadhna Lal; Suvradeep Mitra
Abstract
We documented the presence of both mature and immature hyaline cartilage in the portal plate and the wall of the gallbladder in a 2-month-old girl infant with BA who had undergone Kasai portoenterostomy.
The presence of cartilage could be part of a heterotopia or an uncommon connective tissue metaplasia. The presence of immature cartilage with the merging of the perichondrium with the soft tissue highlights a metaplastic etiology in the index case.
Keywords
References
1 Ayyanar P, Mahalik SK, Pati AB, Mitra S. The presence of pericholedochal hyaline cartilage in biliary atresia: a report and a review. Fetal Pediatr Pathol. 2020;39(2):156-62.
2 Stahlschmidt J, Stringer MD, Wyatt J, Davison S, Rajwal S, McClean P. Histologic oddities at the porta hepatis in biliary atresia. J Pediatr Surg. 2008;43(7):1328-32.
3 Hassab MH, Baez-Giangreco A, Afzal M, Shadi SM, Al Olayet YF. Extrahepatic biliary atresia with hyaline cartilage and multiple congenital anomalies: a case report. Saudi J Gastroenterol. 1996;2(3):156-9. PMid:19864825.
4 Mirkin LD, Knisely AS. Hyaline cartilage at porta hepatis in extrahepatic biliary atresia. Pediatr Pathol Lab Med. 1997;17(4):587-91.
5 Kashiwagi Y, Kawashima H, Ioi H, et al. Biliary atresia with cartilage formation. Pediatr Int. 2007;49(5):683-5.
6 Altamirano E, Drut R. Extrahepatic biliary atresia with cartilaginous metaplasia in the gallbladder remnants. J Clin Pathol. 2008;61(8):965-6.
7 Vij M, Bachina P, Safwan M. Portal plate with hyaline cartilage in biliary atresia. Indian J Pediatr. 2016;83(2):185-6.
8 Gupta RK, Batra VV, Sengar M, Sakhuja P, Rooge SN. Biliary atresia with hyaline cartilage at the porta hepatis. Ann Pediatr Surg. 2016;12(3):122-5.
9 Elhence P, Sinha A. Hyaline cartilage at porta hepatis in extrahepatic biliary atresia: metaplasia or choristoma. Sudan J Paediatr. 2020;20(1):73-6.
10 Hartley JL, Davenport M, Kelly DA. Biliary atresia. Lancet. 2009;374(9702):1704-13.
11 Mitra S, Ayyanar P, Mahalik SK, Patra S, Purkait S, Satapathy AK. Diminution of the primary cilia from the intrahepatic cholangiocytes in a pediatric choledochal cyst. Appl Immunohistochem Mol Morphol. 2021;29(10):773-80.
12 Zhao D, Long XD, Xia Q. Recent advances in etiology of biliary atresia. Clin Pediatr. 2015;54(8):723-31.
Submitted date:
01/09/2024
Accepted date:
02/28/2024
Publication date:
04/04/2024