Sebaceous breast carcinoma
Natália Nobre de Alencar; Diego Agra de Souza; Alexandre Alves Lourenço; Raimunda Ribeiro da Silva
Abstract
, surrounded by smaller oval-to-fusiform cells with eosinophilic cytoplasm without vacuolization. No lymph node metastases were present. The immunohistochemical reactions were positive for GATA3, EMA, CD15, and GCDFP15 (focal staining), and negative for RE, RP, and HER-2. The tumor was classified as triple-negative. Morphologically, the differential diagnoses included skin sebaceous carcinoma, lipid-rich carcinoma, apocrine carcinoma, and glycogen-rich clear cell carcinoma. Most of the previously reported cases were positive for RE and RP, which generally was associated with a better prognosis. However, some cases presented a more aggressive behavior with distant and lymph node metastases.
Keywords
References
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Submitted date:
10/04/2021
Accepted date:
02/15/2022
Publication date:
04/14/2022
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