Autopsy and Case Reports
https://app.periodikos.com.br/journal/autopsy/article/doi/10.4322/acr.2020.213
Autopsy and Case Reports
Autopsy Case Report and Review

Gestational gigantomastia with fatal outcome

Natalia Rakislova; Lucilia Lovane; Fabiola Fernandes; Emília Gonçalves; Quique Bassat; Sibone Mocumbi; Jaume Ordi; Carla Carrilho

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Abstract

ABSTRACT: Gigantomastia is a rare disease defined by an extreme and rapid enlargement of the breast, generally bilateral. The majority of cases are reported in pregnant women. Ninety-eight cases of gestational gigantomastia have been identified in electronic databases, and those with fatal outcomes comprised only 2 cases (2%). Despite its benign nature, it can lead to severe complications and even death. Its etiology has not been fully elucidated, but it has been speculated that a hormonal component may play a role in the pathogenesis. Currently, treatment options are limited, and surgery is gaining importance, but it is often not feasible in low-resource settings. Herein, we describe a case of a 30-year-old HIV-positive female with no relevant past medical history, who died due to the complications of gestational gigantomastia at the Maputo Central Hospital, in Mozambique.

Keywords

Gigantomastia, Breast Diseases, Pregnancy, Pregnancy Complications, HIV

References

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Submitted date:
06/20/2020

Accepted date:
07/20/2020

Publication date:
11/20/2020

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