Hepatoid adenocarcinoma of the lung is a rare subtype of lung cancer. We report a case of a metastatic hepatoid adenocarcinoma of the lung with aggressive behavior, including biopsy and autopsy findings. The pulmonary tumors showed features indistinguishable from hepatocellular carcinoma and were diffusely positive for Hepatocyte Paraffin 1.
SunJN, ZhangBL, LiLK, YuHY, WangB. Hepatoid adenocarcinoma of the lung without production of alpha-fetoprotein: a case report and review of the literature.
KishimotoT, YanoT, HiroshimaK, InayamaY, KawachiK, NakataniY. A case of α-fetoprotein–producing pulmonary carcinoma with restricted expression of hepatocyte nuclear factor-4α in hepatoid foci: a case report with studies of previous cases.
TerraccianoLM, GlatzK, MhawechP, et al. Hepatoid adenocarcinoma with liver metastasis mimicking hepatocellular carcinoma: an immunohistochemical and molecular study of eight cases.
BasseV, SchickU, GueguenP, et al. A mismatch repair-deficient hepatoid adenocarcinoma of the lung responding to Anti-PD-L1 durvalumab therapy despite no PD-L1 expression.
FanZ, van de RijnM, MontgomeryK, RouseRV. Hep par 1 antibody stain for the differential diagnosis of hepatocellular carcinoma: 676 tumors tested using tissue microarrays and conventional tissue sections.
PanCC, ChenPC, TsaySH, ChiangH. Cytoplasmic immunoreactivity for thyroid transcription factor-1 in hepatocellular carcinoma: a comparative immunohistochemical analysis of four commercial antibodies using a tissue array technique.
CarlinfanteG, FoschiniMP, PasquinelliG, ScottiR, CavazzaA. Hepatoid carcinoma of the lung: a case report with immunohistochemical, ultrastructural and in-situ hybridization findings.