The colon is a rare site of occurrence of liposarcoma, as either the primary site or by secondary involvement from a retroperitoneal liposarcoma. Liposarcomatosis denotes simultaneous occurrence of multiple liposarcomas. There are only 17 cases of primary colonic liposarcoma reported in the English literature—one of which was primary colonic liposarcomatosis. We depict the second case of primary colonic liposarcomatosis in a 57-year-old female who presented with abdominal swelling and pain. On exploratory laparotomy, two large masses were seen arising from the wall of the right colon along with multiple smaller masses attached to the colon. Right hemicolectomy with en bloc excision of the masses was performed along with hysterectomy and pelvic floor repair. Macroscopically, multiple exophytic masses and one endophytic mass were identified. The exophytic masses were of variable size and were found to hang from the colon by a thin pedicle simulating variable-sized appendices epiploicae. Histopathologically, the lesions showed the morphology of well-differentiated liposarcoma. This appears to be a case of primary colonic liposarcomatosis. There is only one other similar case reported in the English literature, to the best of our knowledge.
SawayamaH, YoshidaN, MiyamotoY, et al. Primary colonic well-differentiated/dedifferentiated liposarcoma of the ascending colon: a case report. Surg Case Rep. 2017;3(1):96. [https://doi.org/10.1186/s40792-017-0373-4]. [PMID:28856628]
ChoiYY, KimYJ, JinSY. Primary liposarcoma of the ascending colon: a rare case of mixed type presenting as hemoperitoneum combined with other type of retroperitoneal liposarcoma. BMC Cancer. 2010;10(1):239. [https://doi.org/10.1186/1471-2407-10-239]. [PMID:20507577]
DalalKM, KattanMW, AntonescuCR, BrennanMF, SingerS. Subtype specific prognostic nomogram for patients with primary liposarcoma of the retroperitoneum, extremity, or trunk. Ann Surg. 2006;244(3):381-91. [PMID:16926564]
FernandesSR, Rita GoncalvesA, LopesJ, et al. Primary liposarcoma of the sigmoid presenting as colonic intussusception - A case report. Rev Esp Enferm Dig. 2016;108(9):591-4. [PMID:26785977]
KitoY, FujiiT, NishiyamaT, et al. Peduncular liposarcoma of the colon: a case report and literature review. J Gastrointest Cancer. 2014;45(Suppl. 1):248-51. [https://doi.org/10.1007/s12029-014-9647-2]. [PMID:25216753]
YarenA, DegirmenciogluS, Calli DemirkanN, Gokcen DemirayA, TaskoyluB, Gokoz DoguG. Primary mesenchymal tumors of the colon: a report of three cases. Turk J Gastroenterol. 2014;25(3):314-8. [https://doi.org/10.5152/tjg.2014.4010]. [PMID:25141322]
RudnickiC, RomanowskiM, Medrek-SochaM, Stec-MichalskaK. The diagnosis of sigmoid liposarcoma in a young male with metabolic syndrome. J Clin Diagn Res. 2015;9(12):OD01-03. [PMID:26816934]
WoodDL, MorgensternL. Liposarcoma of the ileocecal valve: a case report. Mt Sinai J Med. 1989;56(1):62-4. [PMID:2784186]
ParksRW, MullanFJ, KamelHM, WalshMY, McKelveyST. Liposarcoma of the colon. Ulster Med J. 1994;63(1):111-3. [PMID:8658985]
LewisJJ, LeungD, WoodruffJM, BrennanMF. Retroperitoneal soft-tissue sarcoma: analysis of 500 patients treated and followed at a single institution. Ann Surg. 1998;228(3):355-65. [https://doi.org/10.1097/00000658-199809000-00008]. [PMID:9742918]
HoffmanA, LazarAJ, PollockRE, LevD. New frontiers in the treatment of liposarcoma, a therapeutically resistant malignant cohort. Drug Resist Updat. 2011;14(1):52-66. [https://doi.org/10.1016/j.drup.2010.11.001]. [PMID:21169051]
Facebook
Google+
Twitter
LinkedIn
Mendeley
StumbleUpon
CiteULike
Reddit
Email