Autopsy and Case Reports
https://app.periodikos.com.br/journal/autopsy/article/doi/10.4322/acr.2013.038
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Article / Autopsy Case Report

Wharton’s jelly absence: a possible cause of stillbirth

Eduarda Bittencourt Damasceno; Patrícia Picciarelli de Lima

http://dx.doi.org/10.4322/acr.2013.038 Autops Case Rep, vol.3, n4, p.43-47, 2013
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Abstract

The umbilical cord is a structure that provides vascular flow between the fetus and the placenta. It contains two arteries and one vein, which are surrounded and supported by gelatinous tissue known as Wharton’s jelly. There are many umbilical cord abnormalities that are related to the prognosis of fetus survival and birth weight. The authors report a case of umbilical cord constriction due to the localized absence of Wharton’s jelly, which was undiagnosed antenatally and had a fatal outcome. A review of the association between the absence of Wharton’s jelly and an unfavorable pregnancy outcome was undertaken.
 

Keywords

Umbilical Cord, Wharton Jelly, Stillbirth

References

Gardosi J, Chang A, Kalyan B, Sahota D, Symonds EM. Customised antenatal growth charts. Lancet. 1992;339:283-7. http://dx.doi.org/ [https://doi.org/10.1016/0140-6736(92)91342-6].

Benirschke K, Kaufman P, Baergen RN. Pathology of the human placenta. 5th ed. New York: Springer; 2006.

Moinian M, Meyer WW, Lind J. Diameters of umbilical cord vessels and the weight of the cord in relation to clamping time. Am J Obstet Gynecol. 1969;105:604.

Patel D, Dawson M, Kalyanam P, et al. Umbilical cord circumference at birth. Am J Dis Child. 1989;143:638-9.

Filiz A, Rahine B, Keskin HL, Esra AK. Positive correlation between the quantity of Wharton’s jelly in the umbilical cord and birth weight. Taiwan J Obstet Gynecol. 2011;50:33-6. http://dx.doi.org/ [https://doi.org/10.1016/j.tjog.2009.11.002].

Takechi K, Kuwabane Y, Mizuna M. Ultrastructure and immunohistochemical studies of Wharton’s jelly umbilical cord cells. Placenta. 1993;14:235-45. http://dx.doi.org/ [https://doi.org/10.1016/S0143-4004(05)80264-4].

Labarrere C, Sebastiani M, Siminovich M, Torassa E, Althabe O. Absence of Wharton’s jelly around the umbilical arteries: an unusual cause of perinatal mortality. Placenta. 1985;6:555-9. http://dx.doi.org/ [https://doi.org/10.1016/S0143-4004(85)80010-2].

Di Naro E, Ghezzi F, Raio L, Franchi M, D’Addario V. Umbilical cord morphology and pregnancy outcome. Eur J Obstet Gynecol Reprod Biol. 2001;96:150-7. http://dx.doi.org/ [https://doi.org/10.1016/S0301-2115(00)00470-X].

Proctor LK, Fitzgerald B, Whittle WL, et al. Umbilical cord diameter percentile curves and their correlation to birth weight and placental pathology. Placenta. 2013;34:62-6. http://dx.doi.org/ [https://doi.org/10.1016/j.placenta.2012.10.015].

Silver RK, Dooley SL, Tamura RK, Depp R. Umbilical cord size and amniotic fluid volume in prolonged pregnancy. Am J Obstet Gynecol. 1987;157:716-20. http://dx.doi.org/ [https://doi.org/10.1016/S0002-9378(87)80036-4].

Raio L, Ghezzi F, Di Naro E, et al. Sonographic measurements of the umbilical cord and feftal anthropometric parameters. Eur J Obstet Gynecol Reprod Biol. 1999;83:135-45. http://dx.doi.org/ [https://doi.org/10.1016/S0301-2115(98)00314-5].

Bergman P, Lundin P, Malmstrom T. Mucoid degeneration of the Wharton’s jelly: an umbilical cord threatening foetal life. Acta Obstet Gynecol Scand. 1961;40:372-8. http://dx.doi.org/ [https://doi.org/10.3109/00016346109159935].

Baergen R. Cord abnormalities, structural lesions and cord “accidents”. Semin Diagn Pathol. 2007;24:23-32. http://dx.doi.org/ [https://doi.org/10.1053/j.semdp.2007.02.004].


 

Publication date:
01/13/2016

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